Ternary oxovanadium (IV) complexes of ONO-donor Schiff base and polypyridyl derivatives as protein tyrosine phosphatase inhibitors: synthesis, characterization, and …

C Yuan, L Lu, X Gao, Y Wu, M Guo, Y Li, X Fu… - JBIC Journal of …, 2009 - Springer
A series of oxovanadium complexes with mixed ligands, a tridentate ONO-donor Schiff base
ligand [viz., salicylidene anthranilic acid (SAA)], and a bidentate NN ligand [viz., 2, 2 …

Exploration of α-aminophosphonate N-derivatives as novel, potent and selective inhibitors of protein tyrosine phosphatases

Q Wang, M Zhu, R Zhu, L Lu, C Yuan, S **ng… - European journal of …, 2012 - Elsevier
Seventeen α-aminophosphonates are synthesized. Their compositions and structures are
established by EA, UV, FT-IR, 1H NMR, 13C NMR, 31P NMR and ESI-MS. Compounds 1–4 …

Hypoglycemic effect and mechanism of honokiol on type 2 diabetic mice

J Sun, X Fu, Y Liu, Y Wang, B Huo, Y Guo… - Drug design …, 2015 - Taylor & Francis
Background Honokiol is one of the main bioactive constituents of the traditional Chinese
herbal drug Magnolia bark (Cortex Magnoliae officinalis, Hou Po). The aim of this study was …

Synthesis and evaluation of oxovanadium (IV) complexes of Schiff-base condensates from 5-substituted-2-hydroxybenzaldehyde and 2-substituted-benzenamine as …

H Han, L Lu, Q Wang, M Zhu, C Yuan, S **ng… - Dalton Transactions, 2012 - pubs.rsc.org
Five oxovanadium (IV) complexes, which were divided into two groups,[VIVO (bhbb,
nhbb)(H2O) 2](tridentate ligands: H2bhbb= 2-(5-bromo-2-hydroxylbenzylideneamino) …

A dioxidovanadium (V) complex of NNO-donor Schiff base as a selective inhibitor of protein tyrosine phosphatase 1B: Synthesis, characterization, and biological …

Y Jia, L Lu, M Zhu, C Yuan, S **ng, X Fu - European Journal of Medicinal …, 2017 - Elsevier
A new dioxidovanadium (V) complex, VO 2 (HPPCH)(1)(H 2 PPCH= N'-picolinoylpyridin-1-
ium-2-carbohydrazonate) has been synthesized and characterized by elemental analysis …

Magnolia officinalis Extract Contains Potent Inhibitors against PTP1B and Attenuates Hyperglycemia in db/db Mice

J Sun, Y Wang, X Fu, Y Chen, D Wang… - BioMed Research …, 2015 - Wiley Online Library
Protein tyrosine phosphatase 1B (PTP1B) is an established therapeutic target for type 2
diabetes mellitus (T2DM) and obesity. The aim of this study was to investigate the inhibitory …

Potent inhibition of protein tyrosine phosphatases by quinquedentate binuclear copper complexes: synthesis, characterization and biological activities

Q Wang, M Zhu, L Lu, C Yuan, S **ng, X Fu - Dalton Transactions, 2011 - pubs.rsc.org
Three phosphono-containing multidentate ligands were employed to synthesize
quinquedentate binuclear copper complexes,[Cu2L2](1–3)(H2L1= diethyl (propane-1, 3 …

Mononuclear copper (II) complexes with 3, 5-substituted-4-salicylidene-amino-3, 5-dimethyl-1, 2, 4-triazole: synthesis, structure and potent inhibition of protein tyrosine …

L Ma, L Lu, M Zhu, Q Wang, Y Li, S **ng, X Fu… - Dalton …, 2011 - pubs.rsc.org
Six copper complexes of Schiff base ligands containing 3, 5-substituted-4-salicylideneamino-
3, 5-dimethyl-1, 2, 4-triazole have been synthesized and well characterized. The structures …

Potent inhibition of protein tyrosine phosphatases by copper complexes with multi-benzimidazole derivatives

Y Li, L Lu, M Zhu, Q Wang, C Yuan, S **ng, X Fu, Y Mei - Biometals, 2011 - Springer
A series of copper complexes with multi-benzimidazole derivatives, including mono-and di-
nuclear, were synthesized and characterized by Fourier transform IR spectroscopy, UV–Vis …

Dinuclear copper complexes of organic claw: potent inhibition of protein tyrosine phosphatases

L Ma, L Lu, M Zhu, Q Wang, F Gao, C Yuan… - Journal of Inorganic …, 2011 - Elsevier
Three dinuclear copper complexes of organic claw ligands (2, 2′, 2 ″, 2‴-(5-R-2-hydroxy-
1, 3-phenylene) bis (methylene) bis (azanetriyl) tetraacetic acid, R= methyl (H5L1), chloro …