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Artificial intelligence-based toxicity prediction of environmental chemicals: future directions for chemical management applications
Recently, research on the development of artificial intelligence (AI)-based computational
toxicology models that predict toxicity without the use of animal testing has emerged …
toxicology models that predict toxicity without the use of animal testing has emerged …
Data-driven machine learning in environmental pollution: gains and problems
The complexity and dynamics of the environment make it extremely difficult to directly predict
and trace the temporal and spatial changes in pollution. In the past decade, the …
and trace the temporal and spatial changes in pollution. In the past decade, the …
Remediation and toxicity of endocrine disruptors: a review
RS Monisha, RL Mani, B Sivaprakash… - Environmental …, 2023 - Springer
Endocrine disruptors are hazardous chemicals with chronic health effects for most living
organisms, inducing homeostasis, hormonal imbalances, cancer, reproductive and …
organisms, inducing homeostasis, hormonal imbalances, cancer, reproductive and …
Computational pharmacology and computational chemistry of 4-hydroxyisoleucine: Physicochemical, pharmacokinetic, and DFT-based approaches
Computational pharmacology and chemistry of drug-like properties along with
pharmacokinetic studies have made it more amenable to decide or predict a potential drug …
pharmacokinetic studies have made it more amenable to decide or predict a potential drug …
Detection of epileptic seizure using EEG signals analysis based on deep learning techniques
The brain neurons' electrical activities represented by Electroencephalogram (EEG) signals
are the most common data for diagnosing Epilepsy seizure, which is considered a chronic …
are the most common data for diagnosing Epilepsy seizure, which is considered a chronic …
Data-driven quantitative structure–activity relationship modeling for human carcinogenicity by chronic oral exposure
Traditional methodologies for assessing chemical toxicity are expensive and time-
consuming. Computational modeling approaches have emerged as low-cost alternatives …
consuming. Computational modeling approaches have emerged as low-cost alternatives …
Transformers enable accurate prediction of acute and chronic chemical toxicity in aquatic organisms
Environmental hazard assessments are reliant on toxicity data that cover multiple organism
groups. Generating experimental toxicity data is, however, resource-intensive and time …
groups. Generating experimental toxicity data is, however, resource-intensive and time …
Revealing adverse outcome pathways from public high-throughput screening data to evaluate new toxicants by a knowledge-based deep neural network approach
Traditional experimental testing to identify endocrine disruptors that enhance estrogenic
signaling relies on expensive and labor-intensive experiments. We sought to design a …
signaling relies on expensive and labor-intensive experiments. We sought to design a …
Hybrid non-animal modeling: A mechanistic approach to predict chemical hepatotoxicity
Develo** mechanistic non-animal testing methods based on the adverse outcome
pathway (AOP) framework must incorporate molecular and cellular key events associated …
pathway (AOP) framework must incorporate molecular and cellular key events associated …
Replacement per-and polyfluoroalkyl substances (PFAS) are potent modulators of lipogenic and drug metabolizing gene expression signatures in primary human …
Per-and polyfluoroalkyl substances (PFAS) are a class of environmental toxicants, and
some, such as perfluorooctanesulfonic acid (PFOS) and perfluorooctanoic acid (PFOA) …
some, such as perfluorooctanesulfonic acid (PFOS) and perfluorooctanoic acid (PFOA) …