Structural analysis of ischemic stroke thrombi: histological indications for therapy resistance

S Staessens, F Denorme, O Francois… - …, 2019 - pmc.ncbi.nlm.nih.gov
Ischemic stroke is caused by a thromboembolic occlusion of cerebral arteries. Treatment is
focused on fast and efficient removal of the occluding thrombus, either via intravenous …

Studying stroke thrombus composition after thrombectomy: what can we learn?

S Staessens, O François, W Brinjikji, KM Doyle… - Stroke, 2021 - Am Heart Assoc
The composition of ischemic stroke thrombi has gained an increasing amount of interest in
recent years. The implementation of endovascular procedures in standard stroke care has …

Characterising acute ischaemic stroke thrombi: insights from histology, imaging and emerging impedance-based technologies

S Patil, J Darcourt, P Messina, F Bozsak… - Stroke and Vascular …, 2022 - svn.bmj.com
Treatment of acute ischaemic stroke (AIS) focuses on rapid recanalisation of the occluded
artery. In recent years, advent of mechanical thrombectomy devices and new procedures …

Mechanical characterization of thrombi retrieved with endovascular thrombectomy in patients with acute ischemic stroke

N Boodt, PRW Snouckaert van Schauburg, HM Hund… - Stroke, 2021 - Am Heart Assoc
Background and Purpose: Mechanical properties of thromboemboli play an important role in
the efficacy of endovascular thrombectomy (EVT) for acute ischemic stroke. However, very …

Per-pass analysis of acute ischemic stroke clots: impact of stroke etiology on extracted clot area and histological composition

S Fitzgerald, R Rossi, OM Mereuta, D Jabrah… - Journal of …, 2021 - jnis.bmj.com
Background Initial studies investigating correlations between stroke etiology and clot
composition are conflicting and do not account for clot size as determined by area …

Mechanical behavior of in vitro blood clots and the implications for acute ischemic stroke treatment

S Johnson, J Chueh, MJ Gounis, R McCarthy… - Journal of …, 2020 - jnis.bmj.com
Background Clot mechanical properties are influenced by composition and the arrangement
of components within the clot. This work investigates the effects of platelet-driven contraction …

Applicability assessment of a stent-retriever thrombectomy finite-element model

G Luraghi, JF Rodriguez Matas, G Dubini… - Interface …, 2021 - royalsocietypublishing.org
An acute ischaemic stroke appears when a blood clot blocks the blood flow in a cerebral
artery. Intra-arterial thrombectomy, a mini-invasive procedure based on stent technology, is …

Hyperdense vessel sign as a potential guide for the choice of stent retriever versus contact aspiration as first-line thrombectomy strategy

MH Mohammaden, DC Haussen… - Journal of …, 2021 - jnis.bmj.com
Background The first-pass effect (FPE) has emerged as a key metric for efficacy in
mechanical thrombectomy (MT). The hyperdense vessel sign (HDVS) on non-contrast head …

Diverse thrombus composition in thrombectomy stroke patients with longer time to recanalization

M Abbasi, JA Larco, MO Mereuta, Y Liu, S Fitzgerald… - Thrombosis research, 2022 - Elsevier
Background and purpose Delayed time to recanalization is associated with reduced
recanalization success of mechanical thrombectomy (MT) and thrombolysis in acute …

Thrombus heterogeneity in ischemic stroke

S Staessens, SF De Meyer - Platelets, 2021 - Taylor & Francis
The structure of stroke thrombi has gained an increasing amount of interest in recent years.
The advent of endovascular thrombectomy has offered the unique opportunity to provide …