Cardiomyocyte maturation: advances in knowledge and implications for regenerative medicine

E Karbassi, A Fenix, S Marchiano, N Muraoka… - Nature Reviews …, 2020 - nature.com
Our knowledge of pluripotent stem cell (PSC) biology has advanced to the point where we
now can generate most cells of the human body in the laboratory. PSC-derived …

[HTML][HTML] A review of protocols for human iPSC culture, cardiac differentiation, subtype-specification, maturation, and direct reprogramming

DM Lyra-Leite, Ó Gutiérrez-Gutiérrez, M Wang, Y Zhou… - STAR protocols, 2022 - Elsevier
The methods for the culture and cardiomyocyte differentiation of human embryonic stem
cells, and later human induced pluripotent stem cells (hiPSC), have moved from a complex …

Engineering adolescence: maturation of human pluripotent stem cell–derived cardiomyocytes

X Yang, L Pabon, CE Murry - Circulation research, 2014 - ahajournals.org
The discovery of human pluripotent stem cells (hPSCs), including both human embryonic
stem cells and human-induced pluripotent stem cells, has opened up novel paths for a wide …

High-throughput screening of tyrosine kinase inhibitor cardiotoxicity with human induced pluripotent stem cells

A Sharma, PW Burridge, WL McKeithan… - Science translational …, 2017 - science.org
Tyrosine kinase inhibitors (TKIs), despite their efficacy as anticancer therapeutics, are
associated with cardiovascular side effects ranging from induced arrhythmias to heart …

Cardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat hearts

MA Laflamme, KY Chen, AV Naumova… - Nature …, 2007 - nature.com
Cardiomyocytes derived from human embryonic stem (hES) cells potentially offer large
numbers of cells to facilitate repair of the infarcted heart. However, this approach has been …