The formation of new blood vessels, or angiogenesis, is a complex process that plays
important roles in growth and development, tissue and organ regeneration, as well as …

Diabetic retinopathy is the most frequently occurring complication of diabetes mellitus and
remains a leading cause of vision loss globally. Its aetiology and pathology have been …

Extensive efforts are devoted to refining metal sites for optimizing the catalytic performance
of single‐atom nanozymes (SANzymes), while the contribution of the defect environment of …

Abstract Development of the retinal vasculature is based on highly coordinated signalling
between different cell types of the retina, integrating internal metabolic requirements with …

Aberrant neovascularization contributes to diseases such as cancer, blindness and
atherosclerosis, and is the consequence of inappropriate angiogenic signalling. Although …

The immature retinas of preterm neonates are susceptible to insults that disrupt
neurovascular growth, leading to retinopathy of prematurity. Suppression of growth factors …

The mouse retina has been used extensively over the past decades to study both
physiologic and pathologic angiogenesis. Over time, various mouse retina models have …

Abstract Hypoxia-inducible factor-1α (HIF-1α) mediates hypoxic responses and regulates
gene expression involved in angiogenesis, invasion and metabolism. Among the various …

The Wnt signaling pathway plays a pivotal role in vascular morphogenesis in various organs
including the eye. Wnt ligands and receptors are key regulators of ocular angiogenesis both …

The retina is a powerful experimental system for the analysis of angiogenic blood vessel
growth in the postnatal organisms. The three-dimensional architecture of the vessel network …