Recent substantial evidence implicating commensal bacteria in human diseases has given
rise to a new domain in biomedical research: microbiome medicine. This emerging field …

Enzymes can be engineered at the level of their amino acid sequences to optimize key
properties such as expression, stability, substrate range, and catalytic efficiency─ or even to …

Recent work suggests that AlphaFold (AF)–a deep learning-based model that can
accurately infer protein structure from sequence–may discern important features of folded …

Background Prokaryotic microbes have impacted marine biogeochemical cycles for billions
of years. Viruses also impact these cycles, through lysis, horizontal gene transfer, and …

With protein databases growing rapidly due to advances in structural and computational
biology, the ability to accurately align and rapidly search protein structures has become …

Until recently, the data on the diversity of the entire microbial community from the Baltic Sea
were relatively rare and very scarce. However, modern molecular methods have provided …

The human microbiome emerges as a promising reservoir for diagnostic markers and
therapeutics. Since host-associated microbiomes at various body sites differ and diseases …

Recent work suggests that AlphaFold2 (AF2)–a deep learning-based model that can
accurately infer protein structure from sequence–may discern important features of folded …

The influential concept of the rare biosphere in microbial ecology has underscored the
importance of taxa occurring at low abundances yet potentially playing key roles in …

In a recent paper, we used soil metagenomes from global biomes to assess life history
strategies across soil bacterial communities 1. We compiled 102 traits in a multi-table …