Thioredoxin reductase (TrxR) participates in the regulation of redox reactions in organisms.
It works mainly via its substrate molecule, thioredoxin, to maintain the redox balance and …

The tissue factor (TF) pathway plays a central role in hemostasis and thrombo‐inflammatory
diseases. Although structure‐function relationships of the TF initiation complex are …

Venous and arterial thromboses, called as cancer-associated thromboembolism (CAT), are
common complications in cancer patients that are associated with high mortality. The cell …

The failure of mechanisms of natural anti-coagulation either due to genetic impairment or
due to severe external injuries may result in a condition called thrombosis. This is believed …

Venous thromboembolism (VTE) refers to deep vein thrombosis (DVT), whose consequence
may be a pulmonary embolism (PE). Thrombosis is associated with significant morbidity and …

Modern analytical methods combined with the modern concepts of redox signaling revealed
4-hydroxy-2-nonenal (4-HNE) as particular growth regulating factor involved in redox …

Tissue factor (TF) plays a central role in haemostasis and thrombosis. Following vascular
damage, vessel wall TF initiates the extrinsic coagulation cascade. TF can also be exposed …

Aging is defined as the accumulation of progressive organ dysfunction. There is much
evidence linking the involvement of oxidative stress in the pathogenesis of aging. With …

Background Hyperactive coagulation might cause dangerous complications such as portal
vein thrombosis and pulmonary embolism after mesenchymal stem/stromal cell (MSC) …

Sorafenib (SFB) has improved the treatment of hepatocellular carcinoma (HCC) and has
fewer severe side effects than other agents used for that purpose. However, due to a lack of …