Several studies have utilized a lipid nanoparticle delivery system to enhance the
effectiveness of mRNA therapeutics and vaccines. However, these nanoparticles are …

RNA therapeutics show a significant breakthrough for the treatment of otherwise incurable
diseases and genetic disorders by regulating disease-related gene expression. The …

Fully targeted mRNA therapeutics necessitate simultaneous organ-specific accumulation
and effective translation. Despite some progress, delivery systems are still unable to fully …

Nanoparticle-based RNA delivery has shown great progress in recent years with the
approval of two mRNA vaccines for Severe Acute Respiratory Syndrome Coronavirus 2 …

Infectious diseases present significant challenges to global health, thereby extensively
affecting both human society and the economy. In recent years, functional probes have …

The remarkable success of messenger RNA (mRNA) vaccines against severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) has propelled the rapid development of …

RNA-based therapeutics have shown great promise in various medical applications,
including cancers, infectious diseases, and metabolic diseases. The recent success of …

Development of mRNA therapeutics necessitates targeted delivery technology, while the
clinically advanced lipid nanoparticles face difficulty for extrahepatic delivery. Herein, we …

Vaccines play a critical role in the prevention of life-threatening infectious disease. However,
the development of effective vaccines against many immune-evading pathogens such as …

Abstract mRNA therapeutics have emerged as powerful tools for cancer immunotherapy in
accordance with their superiority in expressing all sequence‐known proteins in vivo. In …