Over the past few decades, substantial evidence has convincingly revealed the existence of
cancer stem cells (CSCs) as a minor subpopulation in cancers, contributing to an aberrantly …

Quiescent cancer cells (QCCs) are nonproliferating cells arrested in the G0 phase,
characterized by ki67low and p27high. QCCs avoid most chemotherapies, and some …

The c-Myc signaling is a new emerging target in cancer therapy. Activation of c-Myc
signaling leads to cancer growth and invasion in vitro and in vivo. The stability of c-Myc can …

Tumor heterogeneity, in principle, reflects the variation among different cancer cell
populations. It can be termed inter-or intra-tumoral heterogeneity, respectively, based on its …

Quiescent cancer cells (QCCs) are cancer cells that are reversibly suspended in G0 phase
with the ability to re-enter the cell cycle and initiate tumor growth, and, ultimately, cancer …

Quiescent cancer cells (QCCs), also known as dormant cancer cells, resist and survive
chemo-and radiotherapy, resulting in treatment failure and later cancer recurrence when …

Background & Aims The ubiquitin ligase F-box and WD repeat domain-containing 7
(FBXW7) is recognized as a tumor suppressor in many cancer types due to its ability to …

The re-proliferation of quiescent cancer cells is considered to be the primary contributor to
prostate cancer (Pca) recurrence and progression. In this study, we investigated the …

Bicyclic polyprenylated acylphloroglucinols (BPAPs), the principal bioactive benzophenone
products isolated from plants of genera Garcinia and Hypericum, have attracted noticeable …

Cancer recurrence poses a significant challenge. At the cellular level, recurrence takes
place as a result of reactivation of dormant cancer cells residing at G 0 phase. The aim of the …