Measurement of biomarker proteins for point-of-care early detection and monitoring of cancer

JF Rusling, CV Kumar, JS Gutkind, V Patel - Analyst, 2010 - pubs.rsc.org
This critical review evaluates progress toward viable point-of-care protein biomarker
measurements for cancer detection and diagnostics. The ability to measure panels of …

Human body fluid proteome analysis

S Hu, JA Loo, DT Wong - Proteomics, 2006 - Wiley Online Library
The focus of this article is to review the recent advances in proteome analysis of human
body fluids, including plasma/serum, urine, cerebrospinal fluid, saliva, bronchoalveolar …

A systematic review of the association between circulating concentrations of C reactive protein and cancer

K Heikkilä, S Ebrahim, DA Lawlor - Journal of Epidemiology & …, 2007 - jech.bmj.com
The objective of this study was to review and summarise the published evidence for an
association between circulating concentrations of C reactive protein (CRP) and cancer …

Systematic review of the association between circulating interleukin-6 (IL-6) and cancer

K Heikkilä, S Ebrahim, DA Lawlor - European journal of cancer, 2008 - Elsevier
Our aim was to systematically review the epidemiologic evidence for an association of
circulating interleukin-6 (IL-6), an inflammatory cytokine and cancer. We systematically …

Antibody-based proteomics: fast-tracking molecular diagnostics in oncology

DJ Brennan, DP O'connor, E Rexhepaj… - Nature Reviews …, 2010 - nature.com
The effective implementation of personalized cancer therapeutic regimens depends on the
successful identification and translation of informative biomarkers to aid clinical decision …

Applications of antibody array platforms

BB Haab - Current opinion in biotechnology, 2006 - Elsevier
Antibody arrays are valuable for the parallel analysis of multiple proteins in small sample
volumes. The earliest and most widely used application of antibody arrays has been to …

Biomarkers in the clinical diagnosis and management of traumatic brain injury

GW Hergenroeder, JB Redell, AN Moore… - Molecular diagnosis & …, 2008 - Springer
Traumatic brain injury (TBI) is the leading cause of death and disability among young adults.
Numerous safety improvements in the workplace, the addition of airbags to vehicles, and the …

Identification of serum biomarker signatures associated with pancreatic cancer

C Wingren, A Sandström, R Segersvärd, A Carlsson… - Cancer research, 2012 - AACR
Pancreatic cancer is an aggressive disease with poor prognosis, due, in part, to the lack of
disease-specific biomarkers that could afford early and accurate diagnosis. With a …

Microarray methods for protein biomarker detection

HJ Lee, AW Wark, RM Corn - Analyst, 2008 - pubs.rsc.org
The application of protein biomarkers as an aid for the detection and treatment of diseases
has been subject to intensified interest in recent years. The quantitative assaying of protein …

Design of high-density antibody microarrays for disease proteomics: key technological issues

CAK Borrebaeck, C Wingren - Journal of proteomics, 2009 - Elsevier
Antibody-based microarray is a novel proteomic technology setting a new standard for
molecular profiling of non-fractionated complex proteomes. The first generation of antibody …