Neurogenesis in the embryonic and adult brain: same regulators, different roles
N Urbán, F Guillemot - Frontiers in cellular neuroscience, 2014 - frontiersin.org
Neurogenesis persists in adult mammals in specific brain areas, known as neurogenic
niches. Adult neurogenesis is highly dynamic and is modulated by multiple physiological …
niches. Adult neurogenesis is highly dynamic and is modulated by multiple physiological …
Apolipoprotein E and apolipoprotein E receptors: normal biology and roles in Alzheimer disease
Apolipoprotein E (APOE) genotype is the major genetic risk factor for Alzheimer disease
(AD); the ε4 allele increases risk and the ε2 allele is protective. In the central nervous system …
(AD); the ε4 allele increases risk and the ε2 allele is protective. In the central nervous system …
Thyroid hormone receptors in brain development and function
J Bernal - Nature clinical practice Endocrinology & metabolism, 2007 - nature.com
Thyroid hormones are important during development of the mammalian brain, acting on
migration and differentiation of neural cells, synaptogenesis, and myelination. The actions of …
migration and differentiation of neural cells, synaptogenesis, and myelination. The actions of …
Organotypic slice cultures: a technique has come of age
Slices of CNS tissue prepared from young rodents can be maintained in culture for many
weeks to months. The basic requirements are simple: a stable substratum, culture medium …
weeks to months. The basic requirements are simple: a stable substratum, culture medium …
[HTML][HTML] Direct binding of Reelin to VLDL receptor and ApoE receptor 2 induces tyrosine phosphorylation of disabled-1 and modulates tau phosphorylation
T Hiesberger, M Trommsdorff, BW Howell, A Goffinet… - Neuron, 1999 - cell.com
The large extracellular matrix protein Reelin is produced by Cajal-Retzius neurons in
specific regions of the develo** brain, where it controls neuronal migration and …
specific regions of the develo** brain, where it controls neuronal migration and …
Reelin is a ligand for lipoprotein receptors
A signaling pathway involving the extracellular protein Reelin and the intracellular adaptor
protein Disabled-1 (Dab1) controls cell positioning during mammalian brain development …
protein Disabled-1 (Dab1) controls cell positioning during mammalian brain development …
Reelin and brain development
Over the last 50 years, the reeler mutant mouse has become an important model for studying
normal and abnormal development in the cerebral cortex and other regions of the brain …
normal and abnormal development in the cerebral cortex and other regions of the brain …
Alterations of GABAergic signaling in autism spectrum disorders
R Pizzarelli, E Cherubini - Neural plasticity, 2011 - Wiley Online Library
Autism spectrum disorders (ASDs) comprise a heterogeneous group of pathological
conditions, mainly of genetic origin, characterized by stereotyped behavior, marked …
conditions, mainly of genetic origin, characterized by stereotyped behavior, marked …
The medial ganglionic eminence gives rise to a population of early neurons in the develo** cerebral cortex
During development of the neocortex, the marginal zone (layer I) and the subplate (layer VII)
are the first layers to form from a primordial plexiform neoropil. The cortical plate (layers II …
are the first layers to form from a primordial plexiform neoropil. The cortical plate (layers II …
Thyroid hormones and brain development
J Bernal - Vitamins & Hormones, 2005 - Elsevier
The action of thyroid hormones (thyroxine, T4; triiodothyronine, T3) on brain development
and function is gaining renewed interest. It has been known for many years that thyroid …
and function is gaining renewed interest. It has been known for many years that thyroid …