Determination of the three dimensional (3D) structure of a protein can provide important
details about its biological functions and mechanism of action. However, despite their …

Abstract The MPI Bioinformatics Toolkit (https://toolkit. tuebingen. mpg. de) is a free, one-stop
web service for protein bioinformatic analysis. It currently offers 34 interconnected external …

Chemerin is a widely distributed multifunctional secreted protein implicated in immune cell
migration, adipogenesis, osteoblastogenesis, angiogenesis, myogenesis, and glucose …

Bioluminescence methodologies have been extraordinarily useful due to their high
sensitivity, broad dynamic range, and operational simplicity. These capabilities have been …

Nuclear pore complexes are fundamental components of all eukaryotic cells that mediate
nucleocytoplasmic exchange. Determining their 110-megadalton structure imposes a …

The chromatin-remodelling complex SWI/SNF is highly conserved and has critical roles in
various cellular processes, including transcription and DNA-damage repair,. It hydrolyses …

Abstract Model quality estimation is an essential component of protein structure prediction,
since ultimately the accuracy of a model determines its usefulness for specific applications …

We developed LOMETS, a local threading meta-server, for quick and automated predictions
of protein tertiary structures and spatial constraints. Nine state-of-the-art threading programs …

Precursor mRNA (pre-mRNA) splicing proceeds by two consecutive transesterification
reactions via a lariat–intron intermediate. Here we present the 3.8 Å cryo-electron …

Abstract Background Intrinsically unstructured proteins (IUPs) lack a well-defined three-
dimensional structure. Some of them may assume a locally stable structure under specific …