Mechanisms of microtubule organization in differentiated animal cells

A Akhmanova, LC Kapitein - Nature Reviews Molecular Cell Biology, 2022 - nature.com
Microtubules are polarized cytoskeletal filaments that serve as tracks for intracellular
transport and form a scaffold that positions organelles and other cellular components and …

Actin–microtubule crosstalk in cell biology

M Dogterom, GH Koenderink - Nature reviews Molecular cell biology, 2019 - nature.com
The cytoskeleton and its components—actin, microtubules and intermediate filaments—
have been studied for decades, and multiple roles of the individual cytoskeletal …

Microtubule organization, dynamics and functions in differentiated cells

A Muroyama, T Lechler - Development, 2017 - journals.biologists.com
Over the past several decades, numerous studies have greatly expanded our knowledge
about how microtubule organization and dynamics are controlled in cultured cells in vitro …

Microtubule-organizing centers

J Wu, A Akhmanova - Annual review of cell and developmental …, 2017 - annualreviews.org
The organization of microtubule networks is crucial for controlling chromosome segregation
during cell division, for positioning and transport of different organelles, and for cell polarity …

[HTML][HTML] Generation and regulation of microtubule network asymmetry to drive cell polarity

JCM Meiring, BI Shneyer, A Akhmanova - Current opinion in cell biology, 2020 - Elsevier
Microtubules control cell architecture by serving as a scaffold for intracellular transport,
signaling, and organelle positioning. Microtubules are intrinsically polarized, and their …

Cellular logistics: unraveling the interplay between microtubule organization and intracellular transport

M Burute, LC Kapitein - Annual review of cell and …, 2019 - annualreviews.org
Microtubules are core components of the cytoskeleton and serve as tracks for motor protein–
based intracellular transport. Microtubule networks are highly diverse across different cell …

Microtubule minus-end regulation at a glance

A Akhmanova, MO Steinmetz - Journal of cell science, 2019 - journals.biologists.com
Microtubules are cytoskeletal filaments essential for numerous aspects of cell physiology.
They are polarized polymeric tubes with a fast growing plus end and a slow growing minus …

CAMSAP2 organizes a γ-tubulin-independent microtubule nucleation centre through phase separation

T Imasaki, S Kikkawa, S Niwa, Y Saijo-Hamano… - Elife, 2022 - elifesciences.org
Microtubules are dynamic polymers consisting of αβ-tubulin heterodimers. The initial
polymerization process, called microtubule nucleation, occurs spontaneously via αβ-tubulin …

A perinuclear microtubule-organizing centre controls nuclear positioning and basement membrane secretion

Y Zheng, RA Buchwalter, C Zheng, EM Wight… - Nature cell …, 2020 - nature.com
Non-centrosomal microtubule-organizing centres (ncMTOCs) have a variety of roles that are
presumed to serve the diverse functions of the range of cell types in which they are found …

Intestinal epithelial cell polarity defects in disease: lessons from microvillus inclusion disease

K Schneeberger, S Roth… - Disease models & …, 2018 - journals.biologists.com
The intestinal epithelium is a highly organized tissue. The establishment of epithelial cell
polarity, with distinct apical and basolateral plasma membrane domains, is pivotal for both …