Glioma targeted therapy: insight into future of molecular approaches

K Yang, Z Wu, H Zhang, N Zhang, W Wu, Z Wang… - Molecular Cancer, 2022 - Springer
Gliomas are the common type of brain tumors originating from glial cells. Epidemiologically,
gliomas occur among all ages, more often seen in adults, which males are more susceptible …

[HTML][HTML] EANO guidelines on the diagnosis and treatment of diffuse gliomas of adulthood

M Weller, M van den Bent, M Preusser… - Nature reviews Clinical …, 2021 - nature.com
In response to major changes in diagnostic algorithms and the publication of mature results
from various large clinical trials, the European Association of Neuro-Oncology (EANO) …

Diagnostic, therapeutic, and prognostic implications of the 2021 World Health Organization classification of tumors of the central nervous system

S Gritsch, TT Batchelor, LN Gonzalez Castro - Cancer, 2022 - Wiley Online Library
The 2016 revised fourth edition of the World Health Organization (WHO) classification of
central nervous system (CNS) tumors incorporated molecular features with histologic …

Primary brain tumours in adults

MJ van den Bent, M Geurts, PJ French, M Smits… - The Lancet, 2023 - thelancet.com
The most frequent adult-type primary CNS tumours are diffuse gliomas, but a large variety of
rarer CNS tumour types exists. The classification of these tumours is increasingly based on …

Genetic and molecular epidemiology of adult diffuse glioma

AM Molinaro, JW Taylor, JK Wiencke… - Nature Reviews …, 2019 - nature.com
The WHO 2007 glioma classification system (based primarily on tumour histology) resulted
in considerable interobserver variability and substantial variation in patient survival within …

Primary brain tumours in adults

S Lapointe, A Perry, NA Butowski - The Lancet, 2018 - thelancet.com
Primary CNS tumours refer to a heterogeneous group of tumours arising from cells within the
CNS, and can be benign or malignant. Malignant primary brain tumours remain among the …

Vorasidenib, a dual inhibitor of mutant IDH1/2, in recurrent or progressive glioma; results of a first-in-human phase I trial

IK Mellinghoff, M Penas-Prado, KB Peters… - Clinical Cancer …, 2021 - AACR
Abstract Purpose: Lower grade gliomas (LGGs) are malignant brain tumors. Current therapy
is associated with short-and long-term toxicity. Progression to higher tumor grade is …

European Association for Neuro-Oncology (EANO) guideline on the diagnosis and treatment of adult astrocytic and oligodendroglial gliomas

M Weller, M Van Den Bent, JC Tonn, R Stupp… - The lancet …, 2017 - thelancet.com
Summary The European Association for Neuro-Oncology guideline provides
recommendations for the clinical care of adult patients with astrocytic and oligodendroglial …

Central nervous system cancers, version 3.2020, NCCN clinical practice guidelines in oncology

LB Nabors, J Portnow, M Ahluwalia, J Baehring… - Journal of the National …, 2020 - jnccn.org
The NCCN Guidelines for Central Nervous System (CNS) Cancers focus on management of
adult CNS cancers ranging from noninvasive and surgically curable pilocytic astrocytomas …

Isocitrate dehydrogenase (IDH) mutant gliomas: a Society for Neuro-Oncology (SNO) consensus review on diagnosis, management, and future directions

JJ Miller, LN Gonzalez Castro, S McBrayer… - Neuro …, 2023 - academic.oup.com
Isocitrate dehydrogenase (IDH) mutant gliomas are the most common adult, malignant
primary brain tumors diagnosed in patients younger than 50, constituting an important cause …