Staphylococcal biofilm development: structure, regulation, and treatment strategies

K Schilcher, AR Horswill - Microbiology and Molecular Biology …, 2020 - Am Soc Microbiol
In many natural and clinical settings, bacteria are associated with some type of biotic or
abiotic surface that enables them to form biofilms, a multicellular lifestyle with bacteria …

Bacterial persisters: molecular mechanisms and therapeutic development

H Niu, J Gu, Y Zhang - Signal transduction and targeted therapy, 2024 - nature.com
Persisters refer to genetically drug susceptible quiescent (non-growing or slow growing)
bacteria that survive in stress environments such as antibiotic exposure, acidic and …

[BOOK][B] 2019 antibacterial agents in clinical development: an analysis of the antibacterial clinical development pipeline

World Health Organization - 2020 - books.google.com
Some rights reserved. This work is available under the Creative Commons Attribution-
NonCommercial-ShareAlike 3.0 IGO licence (CC BY-NC-SA 3.0 IGO; https …

[HTML][HTML] 2021 antibacterial agents in clinical and preclinical development: an overview and analysis

World Health Organization - 2022 - books.google.com
Page 1 2021 ANTIBACTERIAL AGENTS IN CLINICAL AND PRECLINICAL DEVELOPMENT:
an overview and analysis World Health Organization Page 2 A PRE Page 3 2021 …

Novel antimicrobial agents for combating antibiotic-resistant bacteria

RYK Chang, SC Nang, HK Chan, J Li - Advanced drug delivery reviews, 2022 - Elsevier
Antibiotic therapy has become increasingly ineffective against bacterial infections due to the
rise of resistance. In particular, ESKAPE pathogens (Enterococcus faecium, Staphylococcus …

Staphylococcal biofilms

M Otto - Microbiology spectrum, 2018 - Am Soc Microbiol
Staphylococci, with the leading species Staphylococcus aureus and Staphylococcus
epidermidis, are the most frequent causes of infections on indwelling medical devices. The …

Therapeutic potential of bacteriophage endolysins for infections caused by Gram-positive bacteria

H Liu, Z Hu, M Li, Y Yang, S Lu, X Rao - Journal of biomedical science, 2023 - Springer
Abstract Gram-positive (G+) bacterial infection is a great burden to both healthcare and
community medical resources. As a result of the increasing prevalence of multidrug-resistant …

Potential impact of the multi-target drug approach in the treatment of some complex diseases

XH Makhoba, C Viegas Jr, RA Mosa… - Drug design …, 2020 - Taylor & Francis
It is essential to acknowledge the efforts made thus far to manage or eliminate various
disease burden faced by humankind. However, the rising global trends of the so-called …

Staphylococcal biofilms: Challenges and novel therapeutic perspectives

C Kranjec, D Morales Angeles, M Torrissen Mårli… - Antibiotics, 2021 - mdpi.com
Staphylococci, like Staphylococcus aureus and S. epidermidis, are common colonizers of
the human microbiota. While being harmless in many cases, many virulence factors result in …

Virulence factors in coagulase-negative staphylococci

A França, V Gaio, N Lopes, LDR Melo - Pathogens, 2021 - mdpi.com
Coagulase-negative staphylococci (CoNS) have emerged as major pathogens in healthcare-
associated facilities, being S. epidermidis, S. haemolyticus and, more recently, S …