Atherosclerotic cardiovascular (CV) disease (ASCVD) incidence and mortality rates are
declining in many countries in Europe, but it is still a major cause of morbidity and mortality …

Aims The expression of GADD153 (growth arrest and DNA damage-inducible gene 153), an
apoptosis-regulated gene, increases during endoplasmic reticulum (ER) stress. How …

In the Guidelines, differentiation between optimal and essential standards were not always
possible, and were made in sections where it was most practical and sensible. The …

Document Reviewers: Luis Alcocer (Mexico), Christina Antza (Greece), Mustafa Arici
(Turkey), Eduardo Barbosa (Brazil), Adel Berbari (Lebanon), Luıs Bronze (Portugal), John …

• The specific situation of the patient. Unless otherwise provided for by national regulations,
off-label use of medication should be limited to situations where it is in the patient's interest …

Background Aldosterone synthase controls the synthesis of aldosterone and has been a
pharmacologic target for the treatment of hypertension for several decades. Selective …

SciELO - Brasil - Diretrizes Brasileiras de Hipertensão Arterial – 2020 Diretrizes Brasileiras de
Hipertensão Arterial – 2020 Acessibilidade / Reportar erro Brasil Lista alfabética de periódicos …

Hypertension Canada's 2020 guidelines for the prevention, diagnosis, risk assessment, and
treatment of hypertension in adults and children provide comprehensive, evidence-based …

Background: Primary aldosteronism is a nonsuppressible renin-independent aldosterone
production that causes hypertension and cardiovascular disease. Objective: To characterize …

Excessive adiposity raises blood pressure and accounts for 65–75% of primary
hypertension, which is a major driver of cardiovascular and kidney diseases. In obesity …