The brain requires a continuous supply of energy in the form of ATP, most of which is
produced from glucose by oxidative phosphorylation in mitochondria, complemented by …

Alzheimer disease (AD) is associated with multiple etiologies and pathological mechanisms,
among which oxidative stress (OS) appears as a major determinant. Intriguingly, OS arises …

During aging, the cellular milieu of the brain exhibits tell-tale signs of compromised
bioenergetics, impaired adaptive neuroplasticity and resilience, aberrant neuronal network …

Alzheimer's disease (AD) is a progressive neurodegenerative disease in the elderly with
dementia, memory loss, and severe cognitive impairment that imposes high medical costs …

During evolution, individuals whose brains and bodies functioned well in a fasted state were
successful in acquiring food, enabling their survival and reproduction. With fasting and …

Alzheimer's disease (AD) is a major subtype of neurodegenerative dementia caused by long-
term interactions and accumulation of multiple adverse factors, accompanied by …

Introduction Deteriorating brain glucose metabolism precedes the clinical onset of
Alzheimer's disease (AD) and appears to contribute to its etiology. Ketone bodies, mainly β …

Alzheimer's disease (AD), an elderly neurodegenerative disorder with a high incidence and
progressive memory decline, is one of the most expensive, lethal, and burdening diseases …

Introduction Unlike for glucose, uptake of the brain's main alternative fuel, ketones, remains
normal in mild cognitive impairment (MCI). Ketogenic medium chain triglycerides (kMCTs) …

Alzheimer's disease (AD) is a debilitating disease leading to great social and economic
burdens worldwide. During the past decades, increasing understanding of this disease …