Chronic active lesions (CAL) are an important manifestation of chronic inflammation in
multiple sclerosis and have implications for non-relapsing biological progression. In recent …

Parkinson's disease (PD) is a common neurodegenerative disease, and apart from a few
rare genetic causes, its pathogenesis remains largely unclear. Recent scientific interest has …

This article provides recommendations for implementing QSM for clinical brain research. It is
a consensus of the International Society of Magnetic Resonance in Medicine, Electro …

Introduction In multiple sclerosis (MS), paramagnetic rim lesions (PRLs) on MRI identify a
subset of chronic active lesions (CALs), which have been linked through clinical and …

To separate the contributions of paramagnetic and diamagnetic sources within a voxel, a
magnetic susceptibility source separation method based solely on gradient-echo data has …

Focal lesions in both white and gray matter are characteristic of multiple sclerosis (MS).
Histopathological studies have helped define the main underlying pathological processes …

Background Multiple sclerosis (MS) lesion evolution may involve changes in diamagnetic
myelin and paramagnetic iron. Conventional quantitative susceptibility map** (QSM) can …

In MRI, researchers have long endeavored to effectively visualize myelin distribution in the
brain, a pursuit with significant implications for both scientific research and clinical …

Although the past decade has seen remarkable progress in the evaluation and management
of multiple sclerosis (MS) and its mimics, many diagnostic, prognostic, and treatment …

BACKGROUND AND PURPOSE: Quantitative susceptibility map** is an emerging
method for characterizing tissue composition and studying myelination and iron deposition …