Adipose tissue, colloquially known as" fat," is an extraordinarily flexible and heterogeneous
organ. While historically viewed as a passive site for energy storage, we now appreciate that …

The perception that intracellular lipolysis is a straightforward process that releases fatty
acids from fat stores in adipose tissue to generate energy has experienced major revisions …

Beige fat plays key roles in the regulation of systemic energy homeostasis; however,
detailed mechanisms and safe strategy for its activation remain elusive. In this study, we …

Rather than serving as a mere onlooker, adipose tissue is a complex endocrine organ and
active participant in disease initiation and progression. Disruptions of biological processes …

Trace-amine-associated receptors (TAARs), a group of biogenic amine receptors, have
essential roles in neurological and metabolic homeostasis. They recognize diverse …

The role of β-adrenergic receptors (βARs) in adipose tissue to promote lipolysis and the
release of fatty acids and nonshivering thermogenesis in brown fat has been studied for so …

Obesity imposes a global health threat and calls for safe and effective therapeutic options.
Here, we found that protein-rich diet significantly reduced body fat storage in fruit flies, which …

As a metabolic organ, adipose tissue plays an important role in regulating metabolism. In
adults, most adipose tissue is white adipose tissue (WAT), and excessive expansion of WAT …

Cannabis sativa is known for its therapeutic benefit in various diseases including pain relief
by targeting cannabinoid receptors. The primary component of cannabis, Δ9 …

Highlights•Molecular and cellular signals promoting and inhibiting lipolysis.•Transcriptional
control of lipolysis.•Adipose tissue microenvironment control of lipolysis.•Systemic effects of …