Quantitative metabolomics based on gas chromatography mass spectrometry: status and perspectives

MM Koek, RH Jellema, J van der Greef, AC Tas… - Metabolomics, 2011 - Springer
Metabolomics involves the unbiased quantitative and qualitative analysis of the complete set
of metabolites present in cells, body fluids and tissues (the metabolome). By analyzing …

[HTML][HTML] High-efficiency effect-directed analysis (EDA) advancing toxicant identification in aquatic environments: Latest progress and application status

W Luo, L Chou, Q Cui, S Wei, X Zhang, J Guo - Environment International, 2024 - Elsevier
Facing the great threats to ecosystems and human health posed by the continuous release
of chemicals into aquatic environments, effect-directed analysis (EDA) has emerged as a …

Comprehensive two dimensional gas chromatography review

HJ Cortes, B Winniford, J Luong… - Journal of separation …, 2009 - Wiley Online Library
Advances, developments and applications in 2‐D comprehensive GC (GC× GC) from 2007
through October 2008 are reviewed, with emphasis on modulation, and data handling, and …

Review of chemometric analysis techniques for comprehensive two dimensional separations data

KM Pierce, B Kehimkar, LC Marney, JC Hoggard… - … of Chromatography A, 2012 - Elsevier
Comprehensive two-dimensional (2D) separations, such as comprehensive 2D gas
chromatography (GC× GC), liquid chromatography (LC× LC), and related instrumental …

Urinary metaboty** of bladder cancer using two-dimensional gas chromatography time-of-flight mass spectrometry

KK Pasikanti, K Esuvaranathan, Y Hong… - Journal of proteome …, 2013 - ACS Publications
Cystoscopy is the gold standard clinical diagnosis of human bladder cancer (BC). As
cystoscopy is expensive and invasive, it compromises patients' compliance toward …

Comprehensive two-dimensional gas chromatography in metabolomics

MF Almstetter, PJ Oefner, K Dettmer - Analytical and bioanalytical …, 2012 - Springer
One of the major objectives in metabolomics is the identification of subtle changes in
metabolite profiles as affected by genetic or environmental factors. Comprehensive two …

Qualitative and quantitative approaches in comprehensive two-dimensional gas chromatography

JA Murray - Journal of Chromatography A, 2012 - Elsevier
Comprehensive two-dimensional gas chromatography (GC× GC) offers advantages over
one-dimensional gas chromatography (GC) including, high peak capacity, signal …

Features for non-targeted cross-sample analysis with comprehensive two-dimensional chromatography

SE Reichenbach, X Tian, C Cordero, Q Tao - Journal of Chromatography A, 2012 - Elsevier
This review surveys different approaches for generating features from comprehensive two-
dimensional chromatography for non-targeted cross-sample analysis. The goal of non …

Forensic potential of comprehensive two-dimensional gas chromatography

A Sampat, M Lopatka, M Sjerps, G Vivo-Truyols… - TrAC Trends in …, 2016 - Elsevier
In this study, the application of comprehensive two-dimensional (2D) gas chromatography
(GC× GC) in forensic science is reviewed. The peer-reviewed publications on the forensic …

Semi-automated non-target processing in GC× GC–MS metabolomics analysis: applicability for biomedical studies

MM Koek, FM van der Kloet, R Kleemann, T Kooistra… - Metabolomics, 2011 - Springer
Due to the complexity of typical metabolomics samples and the many steps required to
obtain quantitative data in GC× GC–MS consisting of deconvolution, peak picking, peak …