[HTML][HTML] Opportunities of connectomic neuromodulation

A Horn, MD Fox - Neuroimage, 2020 - Elsevier
The process of altering neural activity–neuromodulation–has long been used to treat
patients with brain disorders and answer scientific questions. Deep brain stimulation in …

White matter variability, cognition, and disorders: a systematic review

SJ Forkel, P Friedrich, M Thiebaut de Schotten… - Brain Structure and …, 2022 - Springer
Inter-individual differences can inform treatment procedures and—if accounted for—have
the potential to significantly improve patient outcomes. However, when studying brain …

Deep brain stimulation of symptom-specific networks in Parkinson's disease

N Rajamani, H Friedrich, K Butenko, T Dembek… - Nature …, 2024 - nature.com
Abstract Deep Brain Stimulation can improve tremor, bradykinesia, rigidity, and axial
symptoms in patients with Parkinson's disease. Potentially, improving each symptom may …

[HTML][HTML] Lead-DBS v3. 0: Map** deep brain stimulation effects to local anatomy and global networks

C Neudorfer, K Butenko, S Oxenford, N Rajamani… - Neuroimage, 2023 - Elsevier
Following its introduction in 2014 and with support of a broad international community, the
open-source toolbox Lead-DBS has evolved into a comprehensive neuroimaging platform …

Optimal deep brain stimulation sites and networks for stimulation of the fornix in Alzheimer's disease

AS Ríos, S Oxenford, C Neudorfer, K Butenko… - Nature …, 2022 - nature.com
Deep brain stimulation (DBS) to the fornix is an investigational treatment for patients with
mild Alzheimer's Disease. Outcomes from randomized clinical trials have shown that …

Map** lesion-related epilepsy to a human brain network

FL Schaper, J Nordberg, AL Cohen, C Lin, J Hsu… - JAMA …, 2023 - jamanetwork.com
Importance It remains unclear why lesions in some locations cause epilepsy while others do
not. Identifying the brain regions or networks associated with epilepsy by map** these …

Communication dynamics in the human connectome shape the cortex-wide propagation of direct electrical stimulation

C Seguin, M Jedynak, O David, S Mansour, O Sporns… - Neuron, 2023 - cell.com
Communication between gray matter regions underpins all facets of brain function. We study
inter-areal communication in the human brain using intracranial EEG recordings, acquired …

Toward personalized medicine in connectomic deep brain stimulation

B Hollunder, N Rajamani, SH Siddiqi, C Finke… - Progress in …, 2022 - Elsevier
At the group-level, deep brain stimulation leads to significant therapeutic benefit in a
multitude of neurological and neuropsychiatric disorders. At the single-patient level …

Proceedings of the eighth annual deep brain stimulation think tank: advances in optogenetics, ethical issues affecting DBS research, neuromodulatory approaches for …

V Vedam-Mai, K Deisseroth, J Giordano… - Frontiers in Human …, 2021 - frontiersin.org
We estimate that 208,000 deep brain stimulation (DBS) devices have been implanted to
address neurological and neuropsychiatric disorders worldwide. DBS Think Tank presenters …

Comparative connectivity correlates of dystonic and essential tremor deep brain stimulation

T Tsuboi, JK Wong, RS Eisinger, L Okromelidze… - Brain, 2021 - academic.oup.com
The pathophysiology of dystonic tremor and essential tremor remains partially understood.
In patients with medication-refractory dystonic tremor or essential tremor, deep brain …