Evolution of the human nervous system function, structure, and development
The nervous system—in particular, the brain and its cognitive abilities—is among humans'
most distinctive and impressive attributes. How the nervous system has changed in the …
most distinctive and impressive attributes. How the nervous system has changed in the …
Cortical evolution: judge the brain by its cover
To understand the emergence of human higher cognition, we must understand its biological
substrate—the cerebral cortex, which considers itself the crowning achievement of evolution …
substrate—the cerebral cortex, which considers itself the crowning achievement of evolution …
Current advances in primate genomics: novel approaches for understanding evolution and disease
Primate genomics holds the key to understanding fundamental aspects of human evolution
and disease. However, genetic diversity and functional genomics data sets are currently …
and disease. However, genetic diversity and functional genomics data sets are currently …
Comparative primate genomics: emerging patterns of genome content and dynamics
J Rogers, RA Gibbs - Nature Reviews Genetics, 2014 - nature.com
Advances in genome sequencing technologies have created new opportunities for
comparative primate genomics. Genome assemblies have been published for various …
comparative primate genomics. Genome assemblies have been published for various …
Metabolic methanol: molecular pathways and physiological roles
Methanol has been historically considered an exogenous product that leads only to
pathological changes in the human body when consumed. However, in normal, healthy …
pathological changes in the human body when consumed. However, in normal, healthy …
Genome-wide parent-of-origin DNA methylation analysis reveals the intricacies of human imprinting and suggests a germline methylation-independent mechanism of …
C Tayama, V Romanelli, A Martin-Trujillo… - Genome …, 2014 - genome.cshlp.org
Differential methylation between the two alleles of a gene has been observed in imprinted
regions, where the methylation of one allele occurs on a parent-of-origin basis, the inactive …
regions, where the methylation of one allele occurs on a parent-of-origin basis, the inactive …
Evolution of DNA methylation in the human brain
DNA methylation is a critical regulatory mechanism implicated in development, learning,
memory, and disease in the human brain. Here we have elucidated DNA methylation …
memory, and disease in the human brain. Here we have elucidated DNA methylation …
Differences between human and chimpanzee genomes and their implications in gene expression, protein functions and biochemical properties of the two species
MV Suntsova, AA Buzdin - BMC genomics, 2020 - Springer
Chimpanzees are the closest living relatives of humans. The divergence between human
and chimpanzee ancestors dates to approximately 6, 5–7, 5 million years ago. Genetic …
and chimpanzee ancestors dates to approximately 6, 5–7, 5 million years ago. Genetic …
Human brain evolution: transcripts, metabolites and their regulators
What evolutionary events led to the emergence of human cognition? Although the genetic
differences separating modern humans from both non-human primates (for example …
differences separating modern humans from both non-human primates (for example …
Genetic–epigenetic interactions in cis: a major focus in the post-GWAS era
Studies on genetic–epigenetic interactions, including the map** of methylation
quantitative trait loci (mQTLs) and haplotype-dependent allele-specific DNA methylation …
quantitative trait loci (mQTLs) and haplotype-dependent allele-specific DNA methylation …