Towards enhanced functionality of vagus neuroprostheses through in silico optimized stimulation

F Ciotti, R John, N Katic Secerovic, N Gozzi… - Nature …, 2024 - nature.com
Bioelectronic therapies modulating the vagus nerve are promising for cardiovascular,
inflammatory, and mental disorders. Clinical applications are however limited by side-effects …

Multifaceted understanding of human nerve implants to design optimized electrodes for bioelectronics

G Valle, G Aiello, F Ciotti, P Cvancara, T Martinovic… - Biomaterials, 2022 - Elsevier
Bioelectronic medicine is a promising venue for treatment of disabilities using implantable
neural interfaces. Peripheral neurostimulation of residual nerves recently enabled multiple …

Symbiotic electroneural and musculoskeletal framework to encode proprioception via neurostimulation: ProprioStim

A Cimolato, F Ciotti, J Kljajić, G Valle, S Raspopovic - Iscience, 2023 - cell.com
Peripheral nerve stimulation in amputees achieved the restoration of touch, but not
proprioception, which is critical in locomotion. A plausible reason is the lack of means to …

Design of an adaptable intrafascicular electrode (AIR) for selective nerve stimulation by model-based optimization

F Ciotti, A Cimolato, G Valle… - PLOS Computational …, 2023 - journals.plos.org
Peripheral nerve stimulation is being investigated as a therapeutic tool in several clinical
scenarios. However, the adopted devices have restricted ability to obtain desired outcomes …

[HTML][HTML] Selective intrafascicular stimulation of myelinated and unmyelinated nerve fibers through a longitudinal electrode: A computational study

X Wang, Y Zhang, T Guo, S Wu, J Zhong… - Computers in Biology …, 2024 - Elsevier
Carbon nanotube (CNT) fiber electrodes have demonstrated exceptional spatial selectivity
and sustained reliability in the context of intrafascicular electrical stimulation, as evidenced …