Management of musculoskeletal pain: an update with emphasis on chronic musculoskeletal pain

SN El-Tallawy, R Nalamasu, GI Salem, JAK LeQuang… - Pain and therapy, 2021 - Springer
Musculoskeletal pain is a challenging condition for both patients and physicians. Many
adults have experienced one or more episodes of musculoskeletal pain at some time of their …

Discovery and validation of biomarkers to aid the development of safe and effective pain therapeutics: challenges and opportunities

KD Davis, N Aghaeepour, AH Ahn, MS Angst… - Nature Reviews …, 2020 - nature.com
Pain medication plays an important role in the treatment of acute and chronic pain
conditions, but some drugs, opioids in particular, have been overprescribed or prescribed …

Neuropathic pain

L Colloca, T Ludman, D Bouhassira, R Baron… - Nature reviews Disease …, 2017 - nature.com
Neuropathic pain is caused by a lesion or disease of the somatosensory system, including
peripheral fibres (Aβ, Aδ and C fibres) and central neurons, and affects 7–10% of the …

Neuropathic pain: From actual pharmacological treatments to new therapeutic horizons

M Thouaye, I Yalcin - Pharmacology & therapeutics, 2023 - Elsevier
Neuropathic pain, caused by a lesion or disease affecting the somatosensory system, affects
between 3 and 17% of the general population. The treatment of neuropathic pain is …

[HTML][HTML] Neuropathic pain: an updated grading system for research and clinical practice

NB Finnerup, S Haroutounian, P Kamerman, R Baron… - Pain, 2016 - journals.lww.com
The redefinition of neuropathic pain as “pain arising as a direct consequence of a lesion or
disease affecting the somatosensory system,” which was suggested by the International …

Cancer pain assessment and classification

A Caraceni, M Shkodra - Cancers, 2019 - mdpi.com
More than half of patients affected by cancer experience pain of moderate-to-severe
intensity, often in multiple sites, and of different etiologies and underlying mechanisms. The …

Neuropathic pain in the general population: a systematic review of epidemiological studies

O Van Hecke, SK Austin, RA Khan, BH Smith… - PAIN®, 2014 - Elsevier
Most patients with neuropathic pain symptoms present and are managed in primary care,
with only a minority being referred for specialist clinical assessment and diagnoses …

Neuropathic pain: principles of diagnosis and treatment

I Gilron, R Baron, T Jensen - Mayo clinic proceedings, 2015 - Elsevier
Neuropathic pain is caused by disease or injury of the nervous system and includes various
chronic conditions that, together, affect up to 8% of the population. A substantial body of …

The effectiveness of topical cannabidiol oil in symptomatic relief of peripheral neuropathy of the lower extremities

DH Xu, BD Cullen, M Tang… - Current pharmaceutical …, 2020 - benthamdirect.com
Background: Peripheral neuropathy can significantly impact the quality of life for those who
are affected, as therapies from the current treatment algorithm often fail to deliver adequate …

Diabetic neuropathy: clinical manifestations and current treatments

BC Callaghan, HT Cheng, CL Stables… - The lancet …, 2012 - thelancet.com
Diabetic peripheral neuropathy is a prevalent, disabling disorder. The most common
manifestation is distal symmetrical polyneuropathy (DSP), but many patterns of nerve injury …