Bufalin is an endogenous cardiotonic steroid, first discovered in toad venom but also found
in the plasma of healthy humans, with anti-tumour activities in different cancer types. The …

Bufadienolides, specifically bufalin, have garnered attention for their potential therapeutic
application in modulating inflammatory pathways. Bufalin is derived from toad venom and …

TAS2Rs are a family of G protein-coupled receptors that function as bitter taste receptors in
vertebrates. Mammalian TAS2Rs have historically garnered the most attention, leading to …

Background Current approaches used to overcome microbial infections are becoming
inefficient due to the overuse or misuse of antibiotics. Antimicrobial peptides (AMPs) are one …

Introduction: Wound healing is a delicate and complex process influenced by many factors.
The treatment of skin wounds commonly involves the use of wound dressings, which remain …

Toad venom is a traditional Chinese medicine with high medicinal value. The existing
quality evaluation standards of toad venom have obvious limitations because of the lack of …

Skin secretions of toads are a complex mixture of molecules. The substances secreted
comprise more than 80 different compounds that show diverse pharmacological activities …

Background This work aims to analyze the alterations in the levels of PCA3, PCAT1,
PRNCR1, and GAS5 long non-coding RNAs (lncRNAs) after the activation of pDNA-buforin …

This study investigated the morphology of Rhinella crucifer cutaneous glands, as well as the
protein/peptide profiles and bioactivities of body gland secretions (BGS) and parotoid …

Malaria is an infectious disease caused by Plasmodium spp. and it is mainly transmitted to
humans by female mosquitoes of the genus Anopheles. Malaria is an important global …