The corneal stroma plays several pivotal roles within the eye. Optically, it is the main
refracting lens and thus has to combine almost perfect transmission of visible light with …

Cell migration is an adaptive process that depends on and responds to physical and
molecular triggers. Moving cells sense and respond to tissue mechanics and induce …

Kjær, Michael. Role of Extracellular Matrix in Adaptation of Tendon and Skeletal Muscle to
Mechanical Loading. Physiol Rev 84: 649–698, 2004; 10.1152/physrev. 00031.2003.—The …

The fibrous collagens are ubiquitous in animals and form the structural basis of all
mammalian connective tissues, including those of the heart, vasculature, skin, cornea …

As a major component of the human body, the extracellular matrix (ECM) is a complex
biopolymer network. The ECM not only hosts a plethora of biochemical interactions but also …

Collagen constitutes one-third of the human proteome, providing mechanical stability,
elasticity, and strength to organisms and is the prime construction material in biology …

Collagens are triple helical proteins that occur in the extracellular matrix (ECM) and at the
cell–ECM interface. There are more than 30 collagens and collagen-related proteins but the …

Fibril-forming collagens are synthesized in precursor form, procollagens, with N-and C-
terminal propeptide extensions. The C-propeptides direct chain association during …

The tools of recombinant protein expression are now being used to provide recombinant
sources of both collagen and gelatin. The primary focus of this review is to discuss …

Corneal blindness is one of the most common causes of vision loss worldwide, affecting
millions of people. To treat these patients, researchers have been examining different …