Non-lamellar lyotropic liquid crystalline lipid nanoparticles for the next generation of nanomedicine

J Zhai, C Fong, N Tran, CJ Drummond - ACS nano, 2019 - ACS Publications
Nonlamellar lyotropic liquid crystalline (LLC) lipid nanomaterials have emerged as a
promising class of advanced materials for the next generation of nanomedicine, comprising …

Lyotropic liquid crystal engineering moving beyond binary compositional space–ordered nanostructured amphiphile self-assembly materials by design

L van't Hag, SL Gras, CE Conn… - Chemical society …, 2017 - pubs.rsc.org
Ordered amphiphile self-assembly materials with a tunable three-dimensional (3D)
nanostructure are of fundamental interest, and crucial for progressing several biological and …

Preparation, characterization, and antimicrobial activity of cubosome encapsulated metal nanocrystals

TG Meikle, BP Dyett, JB Strachan, J White… - … applied materials & …, 2020 - ACS Publications
Herein, we demonstrate a method for the functionalization of cubic phase lipid nanoparticles
(cubosomes) with a series of magnetite (Fe3O4), copper oxide (Cu2O), and silver (Ag) …

[HTML][HTML] Lipidic lyotropic liquid crystals: Insights on biomedical applications

G Blanco-Fernández, B Blanco-Fernandez… - Advances in Colloid and …, 2023 - Elsevier
Liquid crystals (LCs) possess unique physicochemical properties, translatable into a wide
range of applications. To date, lipidic lyotropic LCs (LLCs) have been extensively explored …

Bicontinuous cubic phase nanoparticle lipid chemistry affects toxicity in cultured cells

TM Hinton, F Grusche, D Acharya, R Shukla… - Toxicology …, 2014 - academic.oup.com
Gaining an increased understanding of the toxicity of new lipid nanoparticle formulations
such as the class of cubic and hexagonal phase forming nanomaterials called cubosomes™ …

In Vitro and In Vivo Toxicity and Biodistribution of Paclitaxel-Loaded Cubosomes as a Drug Delivery Nanocarrier: A Case Study Using an A431 Skin Cancer …

J Zhai, FH Tan, RB Luwor… - ACS Applied Bio …, 2020 - ACS Publications
Cubosomes with an internal three-dimensional (3D) periodic and porous particulate
nanostructure have emerged as a promising drug delivery system for hydrophobic small …

Lipid–PEG conjugates sterically stabilize and reduce the toxicity of phytantriol-based lyotropic liquid crystalline nanoparticles

J Zhai, TM Hinton, LJ Waddington, C Fong, N Tran… - Langmuir, 2015 - ACS Publications
Lyotropic liquid crystalline nanoparticle dispersions are of interest as delivery vectors for
biomedicine. Aqueous dispersions of liposomes, cubosomes, and hexosomes are …

Nanostructured bicontinuous cubic lipid self-assembly materials as matrices for protein encapsulation

CE Conn, CJ Drummond - Soft Matter, 2013 - pubs.rsc.org
We review the use of bicontinuous cubic amphiphile self-assembly materials for protein
encapsulation. The unique amphiphilic nature of bicontinuous cubic lipidic phases make …

Prospective Subunit Nanovaccine against Mycobacterium tuberculosis Infection─Cubosome Lipid Nanocarriers of Cord Factor, Trehalose 6,6′ Dimycolate

S Sarkar, A Mishra, S Periasamy, B Dyett… - … Applied Materials & …, 2023 - ACS Publications
An improved vaccine is urgently needed to replace the now more than 100-year-old Bacillus
Calmette–Guérin (BCG) vaccine against tuberculosis (TB) disease, which represents a …

Effect of cholesterol on biomimetic membrane curvature and coronavirus fusion peptide encapsulation

I Milogrodzka, DT Nguyen Pham, GR Sama… - ACS …, 2023 - ACS Publications
Biomimetic cubic phases can be used for protein encapsulation in a variety of applications
such as biosensors and drug delivery. Cubic phases with a high concentration of cholesterol …