BACKGROUND The genetic composition of embryos generated by in vitro fertilization (IVF)
can be examined with preimplantation genetic testing (PGT). Until recently, PGT was limited …

The genetic and genomic basis of sex differences in blood pressure (BP) traits remain
unstudied at scale. Here, we conducted sex-stratified and combined-sex genome-wide …

As one of the leading causes of premature birth and maternal and infant mortality worldwide,
preeclampsia remains a major unmet public health challenge. Preeclampsia and related …

BACKGROUND: Preeclampsia, a pregnancy-specific condition associated with new-onset
hypertension after 20-weeks gestation, is a leading cause of maternal and neonatal …

Importance Hypertensive disorders of pregnancy (HDPs), including gestational hypertension
and preeclampsia, are important contributors to maternal morbidity and mortality worldwide …

Investigating the genetic factors influencing human birth weight may lead to biological
insights into fetal growth and long-term health. We report analyses of rare variants that …

BACKGROUND: Preeclampsia is a hypertensive disorder of pregnancy characterized by
systemic endothelial dysfunction. The pathophysiology of preeclampsia remains …

Introduction Mortality from preeclampsia (PE) and PE-associated morbidities are 3-to 5-fold
higher in persons of African ancestry than in those of Asian and European ancestries …

Objective Observational studies show that hypertensive disorders of pregnancy (HDPs) are
related to unfavourable maternal cardiovascular disease (CVD) risk profiles later in life. We …

Preeclampsia is a life-threatening complication that develops in 2-8% of pregnancies. It is
characterized by elevated blood pressure after 20 weeks of gestation and may progress to …