Multimodal data integration for oncology in the era of deep neural networks: a review

A Waqas, A Tripathi, RP Ramachandran… - Frontiers in Artificial …, 2024 - frontiersin.org
Cancer research encompasses data across various scales, modalities, and resolutions, from
screening and diagnostic imaging to digitized histopathology slides to various types of …

Prot2text: Multimodal protein's function generation with gnns and transformers

H Abdine, M Chatzianastasis, C Bouyioukos… - Proceedings of the …, 2024 - ojs.aaai.org
In recent years, significant progress has been made in this field of protein function prediction
with the development of various machine-learning approaches. However, most existing …

A systematic review of graph neural network in healthcare-based applications: Recent advances, trends, and future directions

SG Paul, A Saha, MZ Hasan, SRH Noori… - IEEE …, 2024 - ieeexplore.ieee.org
Graph neural network (GNN) is a formidable deep learning framework that enables the
analysis and modeling of intricate relationships present in data structured as graphs. In …

Designing interpretable deep learning applications for functional genomics: a quantitative analysis

A Van Hilten, S Katz, E Saccenti… - Briefings in …, 2024 - academic.oup.com
Deep learning applications have had a profound impact on many scientific fields, including
functional genomics. Deep learning models can learn complex interactions between and …

[HTML][HTML] Proximogram—A multi-omics network-based framework to capture tissue heterogeneity integrating single-cell omics and spatial profiling

SN Krishnan, S Ji, AM Elhossiny, A Rao… - Computers in Biology …, 2024 - Elsevier
The increasing availability of patient-derived multimodal biological data for various diseases
has opened up avenues for finding the optimal methods for jointly leveraging the information …

LASSO–MOGAT: a multi-omics graph attention framework for cancer classification

F Alharbi, A Vakanski, MK Elbashir… - Academia Biology, 2024 - academia.edu
The application of machine learning (ML) methods to analyze changes in gene expression
patterns has recently emerged as a powerful approach in cancer research, enhancing our …

Enhancing Molecular Network‐Based Cancer Driver Gene Prediction Using Machine Learning Approaches: Current Challenges and Opportunities

H Zhang, C Lin, Y Chen, X Shen… - Journal of Cellular …, 2025 - Wiley Online Library
Cancer is a complex disease driven by mutations in the genes that play critical roles in
cellular processes. The identification of cancer driver genes is crucial for understanding …

Comparative Analysis of Multi-Omics Integration Using Advanced Graph Neural Networks for Cancer Classification

F Alharbi, A Vakanski, B Zhang, MK Elbashir… - arxiv preprint arxiv …, 2024 - arxiv.org
Multi-omics data is increasingly being utilized to advance computational methods for cancer
classification. However, multi-omics data integration poses significant challenges due to the …

A controllability reinforcement learning method for pancreatic cancer biomarker identification

Y Wang, J Hong, Y Lu, N Sheng, Y Fu… - IEEE Transactions …, 2024 - ieeexplore.ieee.org
Pancreatic cancer is one of the most malignant cancers with rapid progression and poor
prognosis. The use of transcriptional data can be effective in finding new biomarkers for …

Multilayer network approaches to omics data integration in Digital Twins for cancer research

H Chenel, M Marku, T James, A Zinovyev… - arxiv preprint arxiv …, 2024 - arxiv.org
This review examines current and potential applications of DTs in healthcare, focusing on
the integration of multi-omics data using multilayer network approaches in cancer research …