Their ability to move within genomes gives transposable elements an intrinsic propensity to
affect genome evolution. Non-long terminal repeat (LTR) retrotransposons—including LINE …

Retroelements constitute approximately 45% of the human genome. Long interspersed
nuclear element (LINE) autonomous retrotransposons are predominantly represented by …

SVA is a composite repetitive element named after its main components, SINE, VNTR and
Alu. We have identified 2762 SVA elements from the human genome draft sequence …

Class 2, or DNA transposons, make up∼ 3% of the human genome, yet the evolutionary
history of these elements has been largely overlooked and remains poorly understood. Here …

Mobile elements such as Alu repeats have substantially altered the architecture of the
human genome, and de novo mobile element insertions sometimes cause genetic …

DNA transposons, or class 2 transposable elements, have successfully propagated in a
wide variety of genomes. However, it is widely believed that DNA transposon activity has …

Close to 50% of the human genome harbors repetitive sequences originally derived from
mobile DNA elements, and in normal cells, this sequence compartment is tightly regulated …

The primate order is a monophyletic group thought to have diverged from the Euarchonta
more than 65 mya. 1 Recent paleontological and molecular evolution studies place the last …

The goal of the 1000 Genomes Consortium is to characterize human genome structural
variation (SV), including forms of copy number variations such as deletions, duplications …

Of the 1.1 million Alu retroposons in the human genome, about 10,000 are inserted in the
3′ untranslated regions (UTR) of protein-coding genes and 1% of these (107 events) are …