The role of cancer stem cells in colorectal cancer: from the basics to novel clinical trials

C Hervieu, N Christou, S Battu, M Mathonnet - Cancers, 2021 - mdpi.com
Simple Summary Cancer stem cells (CSCs) fuel tumor growth, metastasis and resistance to
therapy in colorectal cancer (CRC). These cells therefore represent a promising target for …

Single‐cell RNA sequencing and lipidomics reveal cell and lipid dynamics of fat infiltration in skeletal muscle

Z Xu, W You, W Chen, Y Zhou, Q Nong… - Journal of cachexia …, 2021 - Wiley Online Library
Background Ageing is accompanied by sarcopenia and intramuscular fat (IMAT) infiltration.
In skeletal muscle, fat infiltration is a common feature in several myopathies and is …

[PDF][PDF] Mesenchymal stem cells in liver diseases: present status and future perspectives

S Atta, F Megahed, AH Atta - Exp Clin Transplant, 2024 - researchgate.net
Liver disease is a major worldwide health and economic problem. Allograft liver transplant is
the only effective therapy for end-stage liver disease. The shortage of donors, the high costs …

MTH1 suppression enhances the stemness of MCF7 through upregulation of STAT3

J Li, ZH Wang, YM Dang, DN Li, Z Liu, DP Dai… - Free Radical Biology and …, 2022 - Elsevier
MTH1 protein can sanitize the damaged (d) NTP pool and MTH1 inhibitors have been
developed to impede the growth of rapidly proliferating tumor cells; however, the effect of …

New advances of NG2-expressing cell subset in marrow mesenchymal stem cells as novel therapeutic tools for liver fibrosis/cirrhosis

D Hu, J Lai, Q Chen, L Bai - Stem Cell Research & Therapy, 2024 - Springer
Background Bone marrow-derived mesenchymal stem cell (BMMSC)-based therapy has
become a major focus for treating liver fibrosis/cirrhosis. However, although these cell …

Recent technological advancements in stem cell research for targeted therapeutics

N Rai, AK Singh, SK Singh, B Gaurishankar… - Drug Delivery and …, 2020 - Springer
Stem cells have characteristic features of self-renewal, pluripotency and differentiation,
which are responsible for replenishment of tissue or organ. Stem cells are potentiated as …

Effect of selenium on freezing-thawing damage of mice spermatogonial stem cell: a model to preserve fertility in childhood cancers

MB Boroujeni, F Peidayesh, A Pirnia… - Stem Cell …, 2019 - pmc.ncbi.nlm.nih.gov
Background During treatment of childhood cancers, fertility of boys may be affected.
Therefore, freezing spermatogonial stem cell (SSC) is recommended. However, freezing …

Detection of spermatogonial stem/progenitor cells in prepubertal mouse testis with deep learning

B Kahveci, S Önen, F Akal, P Korkusuz - Journal of Assisted Reproduction …, 2023 - Springer
Purpose Rapid and easy detection of spermatogonial stem/progenitor cells (SSPCs) is
crucial for clinicians dealing with male infertility caused by prepubertal testicular damage …

[HTML][HTML] How to Control the Microfluidic Flow and Separate the Magnetic and Non-Magnetic Particles in the Runner of a Disc

YT Lin, CS Huang, SC Tseng - Micromachines, 2021 - mdpi.com
Biochips play an important role in both medical and food industry safety testing. Moreover,
magnetic activated cell sorting is a well-established technology for biochip development …

[PDF][PDF] The role of cancer stem cells in colorectal cancer: from the basics to novel clinical trials. Cancers. 2021; 13: 1092

C Hervieu, N Christou, S Battu, M Mathonnet - 2021 - pdfs.semanticscholar.org
The treatment options available for colorectal cancer (CRC) have increased over the years
and have significantly improved the overall survival of CRC patients. However, the response …