Alzheimer's disease (AD) is the leading cause of dementia worldwide. Individuals affected
by the disease gradually lose their capacity for abstract thinking, understanding …

Varicella zoster virus (VZV) is the causative agent of varicella (chickenpox) and zoster
(shingles). Investigating VZV pathogenesis is challenging as VZV is a human-specific virus …

The fast-growing field of bioelectronic medicine aims to develop engineered systems that
can relieve clinical conditions by stimulating the peripheral nervous system,,,–. This type of …

Severe combined immunodeficiency (SCID) is a primary inherited immunodeficiency
disease that presents before the age of three months and can be fatal. It is usually due to …

Gene therapy is a promising form of treatment for those suffering from neurological disorders
or central nervous system (CNS) injury, however, obstacles remain that limit its translational …

The initial events after DNA virus infection involve a race between epigenetic silencing of the
incoming viral DNA by host cell factors and expression of viral genes. Several host gene …

STING is a nodal point for cellular innate immune response to microbial infections,
autoimmunity and cancer; it triggers the synthesis of the antiviral proteins, type I interferons …

The environment of the central nervous system (CNS) represents a double-edged sword in
the context of viral infections. On the one hand, the infectious route for viral pathogens is …

Over a century ago, the seminal work of Ramón y Cajal revealed that the nervous system is
made of individual units, the neurons, which are related to each other by contiguity rather …

Herpes simplex encephalitis (HSE) is a severe neurological disease in children and adults
caused by herpes simplex virus. This review discusses recent findings on the role of Toll-like …