Cortico-limbic connectivity as a possible biomarker for bipolar disorder: where are we now?
B Vai, C Bertocchi, F Benedetti - Expert review of neurotherapeutics, 2019 - Taylor & Francis
Introduction: The fronto-limbic network has been suggested as a key circuitry in the
pathophysiology and maintenance of bipolar disorder. In the past decade, a disrupted …
pathophysiology and maintenance of bipolar disorder. In the past decade, a disrupted …
[HTML][HTML] Decoding neural circuit dysregulation in bipolar disorder: Toward an advanced paradigm for multidimensional cognitive, emotional, and psychomotor …
L Steardo Jr, M D'Angelo, F Monaco… - Neuroscience & …, 2025 - Elsevier
Bipolar disorder (BD) is characterized by a complex constellation of emotional, cognitive,
and psychomotor disturbances, each deeply intertwined with underlying dysfunctions in …
and psychomotor disturbances, each deeply intertwined with underlying dysfunctions in …
White matter microstructure in youth with and at risk for bipolar disorder
Objectives Bipolar disorder (BD) and familial risk for BD have been associated with aberrant
white matter (WM) microstructure in the corpus callosum and fronto‐limbic pathways. These …
white matter (WM) microstructure in the corpus callosum and fronto‐limbic pathways. These …
Morphological abnormalities in youth with bipolar disorder and their relationship to clinical characteristics
W Li, D Lei, MJ Tallman, JA Welge, TJ Blom… - Journal of Affective …, 2023 - Elsevier
Objectives To characterize the neuroanatomy of BD in youth and its correlation to clinical
characteristics. Methods The current study includes a sample of 105 unmedicated youth with …
characteristics. Methods The current study includes a sample of 105 unmedicated youth with …
Reduced lateral orbitofrontal cortex volume and suicide behavior in youth with bipolar disorder
Objectives Structural abnormalities in cortical and subcortical regions, including the
orbitofrontal cortex (OFC), are altered during brain development in adolescents with bipolar …
orbitofrontal cortex (OFC), are altered during brain development in adolescents with bipolar …
[HTML][HTML] White matter microstructure in individuals with and at risk for bipolar disorder: Evidence for an endophenotype from a voxel-based meta-analysis
Background Aberrant white matter (WM) microstructure has been proposed as a mechanism
underlying bipolar disorder (BD). Given the strong genetic underpinnings of both WM …
underlying bipolar disorder (BD). Given the strong genetic underpinnings of both WM …
White matter microstructure in pediatric bipolar disorder and disruptive mood dysregulation disorder
Objective Disruptive mood dysregulation disorder (DMDD) codifies severe, chronic
irritability. Youths with bipolar disorder (BD) also present with irritability, but with an episodic …
irritability. Youths with bipolar disorder (BD) also present with irritability, but with an episodic …
Towards a neurodevelopmental model of bipolar disorder: a critical review of trait-and state-related functional neuroimaging in adolescents and young adults
Neurodevelopmental mechanisms are increasingly implicated in bipolar disorder (BD),
highlighting the importance of their study in young persons. Neuroimaging studies have …
highlighting the importance of their study in young persons. Neuroimaging studies have …
Longitudinal grey matter changes following first episode mania in bipolar I disorder: a systematic review
Background While widespread grey matter (GM) changes are seen in bipolar I disorder (BD-
I), it is unclear how early in the illness such changes emerge. To date there has been little …
I), it is unclear how early in the illness such changes emerge. To date there has been little …
White matter changes in paediatric bipolar disorder: A systematic review of diffusion magnetic resonance imaging studies
Background Paediatric bipolar disorder (PBD) is characterized by severe mood fluctuations
that deviate from typical childhood emotional development. Despite the efforts, the …
that deviate from typical childhood emotional development. Despite the efforts, the …