The error rate displayed during template copying to produce viral RNA progeny is a
biologically relevant parameter of the replication complexes of viruses. It has consequences …

Evolution of RNA viruses occurs through disequilibria of collections of closely related mutant
spectra or mutant clouds termed viral quasispecies. Here we review the origin of the …

Abstract The B. 1.1. 7 variant (also known as Alpha) of SARS-CoV-2, the cause of the COVID-
19 pandemic, emerged in the UK in the summer of 2020. The prevalence of this variant …

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein
substitution D614G became dominant during the coronavirus disease 2019 (COVID-19) …

How viruses evolve within hosts can dictate infection outcomes; however, reconstructing this
process is challenging. We evaluate our multiplexed amplicon approach, PrimalSeq, to …

Beginning in the summer of 2020, a variant of SARS-CoV-2, the cause of the COVID-19
pandemic, emerged in the United Kingdom (UK). This B. 1.1. 7 variant increased rapidly in …

In experimental evolution, laboratory-controlled conditions select for the adaptation of
species, which can be monitored in real time. Despite the current popularity of such …

Dengue viruses (DENV) are by far the most important arboviral pathogens in the tropics
around the world, putting at risk of infection nearly a third of the global human population …

Mosquitoes develop long-lasting viral infections without substantial deleterious effects,
despite high viral loads. This makes mosquitoes efficient vectors for emerging viral diseases …

Chikungunya virus (CHIKV) is a mosquito-transmitted alphavirus that causes global
epidemics of a debilitating polyarthritis in humans. As there is a pressing need for the …