Carbon monoxide (CO) is an endogenously produced gaseous signaling molecule with
demonstrated pharmacological effects. In studying CO biology, three delivery forms have …

Carbon monoxide has shown promise as a therapeutic agent against cancers. Reactive
oxygen species (ROS)-activated CO prodrugs are highly demanded for targeted cancer …

Myocardial ischaemia reperfusion injury (IRI) occurring from acute coronary artery disease
or cardiac surgical interventions such as bypass surgery can result in myocardial …

With the recognition of the endogenous signaling roles and pharmacological functions of
carbon monoxide (CO), there is an increasing need to understand CO's mechanism of …

Carbon monoxide (CO) is an endogenous signaling molecule with demonstrated
pharmacological effects. For studying CO biology, there is a need for sensitive and selective …

We report a specific lysosome targeted light-responsive CO-releasing molecule (Lyso-
CORM). Lyso-CORM is very stable under dark conditions. CO and singlet oxygen (1O2) …

Parkinson's disease (PD) is a debilitating neurodegenerative disease, with current
treatments primarily focusing on improving dopaminergic activity, providing symptomatic …

Herein, we demonstrate that dichloromethanol but not difluoromethanol is a viable surrogate
of carbon monoxide for prodrug design. A proof of concept was established by the …

Carbon monoxide (CO) is endogenously produced with a range of pharmacological
activities. Sensitive and selective detection of CO is critical to studying its biology. Since the …

Carbon monoxide (CO) is an innate signaling molecule that can regulate immune responses
and interact with crucial elements of the circadian clock. Moreover, pharmacologically, CO …