Drug repurposing is promoted as a cost-and time-effective mechanism for providing new
medicines. Often, however, there is insufficient consideration by academic researchers of …

Human malignancies are one of the major health-related issues though out the world and
anticipated to rise in the future. The development of novel drugs/agents requires a huge …

The development of immune checkpoint inhibitors (ICI) marks an important breakthrough of
cancer therapies in the past years. However, only a limited fraction of patients benefit from …

Purpose: The majority of deaths from breast cancer occur following the development of
metastatic disease, a process inhibited by β-blockers in preclinical studies. This phase II …

An immune response must be tightly controlled so that it will be commensurate with the level
of response needed to protect the organism without damaging normal tissue. The roles of …

Muscle wasting is a serious comorbidity associated with many disorders, including cancer,
kidney disease, heart failure, and aging. Progressive loss of skeletal muscle mass …

Simple Summary Cancer mortalities are growing at an alarming pace around the globe, a
fact related to challenges, such as side effects, selectivity, and resistance, accompanied by …

Purpose The sympathetic nervous system drives breast cancer progression through β-
adrenergic receptor signalling. This discovery has led to the consideration of cardiac β …

The use of already-approved drugs to treat new or alternative diseases has proved to be
beneficial in medicine, because it reduces both drug development costs and timelines. Most …

Drug repurposing is a strategy that aims to develop novel cancer treatments through the
reuse of existing medicines developed in other disease areas. Such a strategy includes the …