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Toxicology and pharmacology of synthetic organoselenium compounds: An update
Here, we addressed the pharmacology and toxicology of synthetic organoselenium
compounds and some naturally occurring organoselenium amino acids. The use of …
compounds and some naturally occurring organoselenium amino acids. The use of …
[HTML][HTML] Selenium and selenoproteins in viral infection with potential relevance to COVID-19
Selenium is a trace element essential to human health largely because of its incorporation
into selenoproteins that have a wide range of protective functions. Selenium has an ongoing …
into selenoproteins that have a wide range of protective functions. Selenium has an ongoing …
[HTML][HTML] Ebselen and analogues: pharmacological properties and synthetic strategies for their preparation
Ebselen is the leader of selenorganic compounds, and starting from its identification as
mimetic of the key antioxidant enzyme glutathione peroxidase, several papers have …
mimetic of the key antioxidant enzyme glutathione peroxidase, several papers have …
Ebselen, a promising antioxidant drug: mechanisms of action and targets of biological pathways
GK Azad, RS Tomar - Molecular biology reports, 2014 - Springer
Ebselen, an organoselenium compound, mimics glutathione peroxidase activity. It is a
multifunctional compound, which catalyzes several essential reactions for the protection of …
multifunctional compound, which catalyzes several essential reactions for the protection of …
Chemical reporters for bacterial glycans: development and applications
Bacteria possess an extraordinary repertoire of cell envelope glycans that have critical
physiological functions. Pathogenic bacteria have glycans that are essential for growth and …
physiological functions. Pathogenic bacteria have glycans that are essential for growth and …
The mycobacterial cell envelope—lipids
M Jackson - Cold Spring Harbor perspectives in …, 2014 - perspectivesinmedicine.cshlp.org
Mycobacterium tuberculosis (Mtb) lipids are indelibly imprinted in just about every key
aspect of tuberculosis (TB) basic and translational research. Although the interest in these …
aspect of tuberculosis (TB) basic and translational research. Although the interest in these …
Small-Molecule Ebselen Binds to YTHDF Proteins Interfering with the Recognition of N6-Methyladenosine-Modified RNAs
M Micaelli, A Dalle Vedove, L Cerofolini… - ACS Pharmacology & …, 2022 - ACS Publications
YTHDF proteins bind the N 6-methyladenosine (m6A)-modified mRNAs, influencing their
processing, stability, and translation. Therefore, the members of this protein family play …
processing, stability, and translation. Therefore, the members of this protein family play …
Rapid detection of Mycobacterium tuberculosis in sputum with a solvatochromic trehalose probe
Tuberculosis (TB) is the leading cause of death from an infectious bacterial disease. Poor
diagnostic tools to detect active disease plague TB control programs and affect patient care …
diagnostic tools to detect active disease plague TB control programs and affect patient care …
The cell envelope glycoconjugates of Mycobacterium tuberculosis
Tuberculosis (TB) remains the second most common cause of death due to a single
infectious agent. The cell envelope of Mycobacterium tuberculosis (Mtb), the causative agent …
infectious agent. The cell envelope of Mycobacterium tuberculosis (Mtb), the causative agent …
Small molecules that sabotage bacterial virulence
The continued rise of antibiotic-resistant bacterial infections has motivated alternative
strategies for target discovery and treatment of infections. Antivirulence therapies function …
strategies for target discovery and treatment of infections. Antivirulence therapies function …