Protein analysis by shotgun/bottom-up proteomics

Y Zhang, BR Fonslow, B Shan, MC Baek… - Chemical …, 2013 - ACS Publications
According to Genome Sequencing Project statistics (http://www. ncbi. nlm. nih.
gov/genomes/static/gpstat. html), as of February 16, 2012, complete gene sequences have …

Fragmentation pathways of protonated peptides

B Paizs, S Suhai - Mass spectrometry reviews, 2005 - Wiley Online Library
The fragmentation pathways of protonated peptides are reviewed in the present paper
paying special attention to classification of the known fragmentation channels into a simple …

Ion activation methods for peptides and proteins

JS Brodbelt - Analytical chemistry, 2016 - ACS Publications
The analysis of peptides and proteins as well as the grander scope of proteomics (large
scale study of proteins) has been advanced by the development of a versatile array of ion …

PepNovo: de novo peptide sequencing via probabilistic network modeling

A Frank, P Pevzner - Analytical chemistry, 2005 - ACS Publications
We present a novel scoring method for de novo interpretation of peptides from tandem mass
spectrometry data. Our scoring method uses a probabilistic network whose structure reflects …

Novor: real-time peptide de novo sequencing software

B Ma - Journal of the American Society for Mass Spectrometry, 2015 - ACS Publications
De novo sequencing software has been widely used in proteomics to sequence new
peptides from tandem mass spectrometry data. This study presents a new software tool …

Deep learning neural network tools for proteomics

JG Meyer - Cell Reports Methods, 2021 - cell.com
Mass-spectrometry-based proteomics enables quantitative analysis of thousands of human
proteins. However, experimental and computational challenges restrict progress in the field …

A method for reducing the time required to match protein sequences with tandem mass spectra

R Craig, RC Beavis - Rapid communications in mass …, 2003 - Wiley Online Library
An algorithm for reducing the time necessary to match a large set of peptide tandem mass
spectra with a list of protein sequences is described. This algorithm breaks the process into …

Proteomic and biochemical analysis of purified human immunodeficiency virus type 1 produced from infected monocyte-derived macrophages

E Chertova, O Chertov, LV Coren, JD Roser… - Journal of …, 2006 - Am Soc Microbiol
Human immunodeficiency virus type 1 (HIV-1) infects CD4+ T lymphocytes and monocytes/
macrophages, incorporating host proteins in the process of assembly and budding. Analysis …

InsPecT: identification of posttranslationally modified peptides from tandem mass spectra

S Tanner, H Shu, A Frank, LC Wang, E Zandi… - Analytical …, 2005 - ACS Publications
Reliable identification of posttranslational modifications is key to understanding various
cellular regulatory processes. We describe a tool, InsPecT, to identify posttranslational …

Reversed-phase liquid chromatography of peptides for bottom-up proteomics: a tutorial

J Lenco, S Jadeja, DK Naplekov… - Journal of Proteome …, 2022 - ACS Publications
The performance of the current bottom-up liquid chromatography hyphenated with mass
spectrometry (LC-MS) analyses has undoubtedly been fueled by spectacular progress in …