Advances in digitizing tissue slides and the fast-paced progress in artificial intelligence,
including deep learning, have boosted the field of computational pathology. This field holds …

Light sheet fluorescence microscopy (LSFM) uses a thin sheet of light to excite only
fluorophores within the focal volume. Light sheet microscopes (LSMs) have a true optical …

Obtaining frozen sections of bone tissue for intraoperative examination is challenging. To
identify the bony edge of resection, orthopaedic oncologists therefore rely on pre-operative …

Pathology is practiced by visual inspection of histochemically stained tissue slides. While the
hematoxylin and eosin (H&E) stain is most commonly used, special stains can provide …

In the past decade, advances in precision oncology have resulted in an increased demand
for predictive assays that enable the selection and stratification of patients for treatment. The …

State-of-the-art tissue-clearing methods provide subcellular-level optical access to intact
tissues from individual organs and even to some entire mammals. When combined with light …

In pathological diagnostics, histological images highlight the oncological features of excised
specimens, but they require laborious and costly staining procedures. Despite recent …

The histological analysis of tissue samples, widely used for disease diagnosis, involves
lengthy and laborious tissue preparation. Here, we show that a convolutional neural network …

The promise of single-objective light-sheet microscopy is to combine the convenience of
standard single-objective microscopes with the speed, coverage, resolution and gentleness …

In oncology, technologies for clinical molecular imaging are used to diagnose patients,
establish the efficacy of treatments and monitor the recurrence of disease. Multiplexed …