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Study of an inhibitory effect of plant polyphenolic compounds against digestive enzymes using bench-working experimental evidence predicted by molecular docking …
K Vyas, S Prabaker, D Prabhu, M Sakthivelu… - International Journal of …, 2024 - Elsevier
The substantial nutritional content and diversified biological activity of plant-based
nutraceuticals are due to polyphenolic chemicals. These chemicals are important and well …
nutraceuticals are due to polyphenolic chemicals. These chemicals are important and well …
Structure-based drug design, molecular dynamics simulation, ADMET, and quantum chemical studies of some thiazolinones targeting influenza neuraminidase
The genetic mutability of the influenza virus leads to the existence of drug-resistant strains
which is dangerous, particularly with the lingering coronavirus disease (COVID-19). This …
which is dangerous, particularly with the lingering coronavirus disease (COVID-19). This …
[HTML][HTML] Synergy, Additive Effects, and Antagonism of Drugs with Plant Bioactive Compounds
N Chaachouay - Drugs and Drug Candidates, 2025 - mdpi.com
Background/Objectives: The interaction of bioactive compounds derived from plants with
drugs has become a significant area of investigation due to its potential to improve, reduce …
drugs has become a significant area of investigation due to its potential to improve, reduce …
Discovery of new 2, 4-diaminopyrimidines derivatives as EGFRT790M kinase inhibitors: a structure-based approach with DFT calculation, drug-likeness, ADME …
Cancer of the lung is known to be the principal cause of tumour-linked mortality worldwide.
Non-small cell lung cancer (NSCLC) is the most common and lethal type of lung cancer with …
Non-small cell lung cancer (NSCLC) is the most common and lethal type of lung cancer with …
Biological activity, chemical composition, and molecular docking of Eugenia punicifolia (Kunth) DC
There is a significant effort to explore the potential pharmacological activity of natural
products derived from plant extracts. The goal is to generate new compounds that could be …
products derived from plant extracts. The goal is to generate new compounds that could be …
Synthesis, fluorescence, enzymes effects, and evaluation of tetrahydroxy substituted zinc phthalocyanine as multitarget metabolic enzyme inhibitors with molecular …
Synthesis and properties of tetrahydroxy substituted zinc phthalocyanine is reported. UV–
Visible spectrum for the aggregation properties of the compound and fluorescence …
Visible spectrum for the aggregation properties of the compound and fluorescence …
[PDF][PDF] Purple Tea (Camellia sinensis var. assamica) Leaves and Obesity Management: A Review of 1, 2-Di-Galloyl-4, 6-Hexahydroxydiphenoyl-β-D-Glucose's (GHG) …
AK Balasubramaniam, A Elangovan, MA Rahman… - Cureus, 2024 - cureus.com
Purple tea (Camellia sinensis var. assamica) is a distinct variety of Camellia sinensis known
for its bioactive compounds, including caffeine, catechins, and a unique compound called 1 …
for its bioactive compounds, including caffeine, catechins, and a unique compound called 1 …
Inhibitory effect of quercetin-3-O-α-rhamnoside, p-coumaric acid, phloridzin and 4-O-β-glucopyranosyl-cis-coumaric acid on rats liver microsomes cytochrome P450 …
C Ma, C Liu, M Ren, L Cui, X **, W Kang - Food and Chemical Toxicology, 2023 - Elsevier
P-coumaric acid, phloridzin, quercetin-3-O-α-rhamnoside and 4-O-β-glucopyranosyl-cis-
coumaric acid isolated in Malus micromalus Makino fruit were investigated the inhibitory …
coumaric acid isolated in Malus micromalus Makino fruit were investigated the inhibitory …
Unveiling 1, 3-thiazine derivative as a potential neuraminidase inhibitor: molecular docking, molecular dynamics, ADMET and DFT studies
The influenza virus is usually influenced by genetic mutations and reassortment of its
different strains, resulting in drug resistance and pandemics. This necessitates the search …
different strains, resulting in drug resistance and pandemics. This necessitates the search …
Comparative studies on the interaction of casticin with five digestive enzymes using multi-spectroscopic methods, enzyme activities, and computational simulations
W Wang, Q Jiang, Y Sun, Y Zhang, Z Zhang… - Journal of Molecular …, 2024 - Elsevier
Casticin, which belongs to the flavonoid class, has been studied extensively due to its
interesting biological activities. α-Amylase, trypsin, α-chymotrypsin, pepsin and lipase are …
interesting biological activities. α-Amylase, trypsin, α-chymotrypsin, pepsin and lipase are …