Radioluminescence in biomedicine: physics, applications, and models

JS Klein, C Sun, G Pratx - Physics in Medicine & Biology, 2019 - iopscience.iop.org
The electromagnetic spectrum contains different frequency bands useful for medical imaging
and therapy. Short wavelengths (ionizing radiation) are commonly used for radiological and …

[HTML][HTML] Inorganic nanoparticles as radiosensitizers for cancer treatment

B Babu, SA Stoltz, A Mittal, S Pawar, E Kolanthai… - Nanomaterials, 2023 - mdpi.com
Nanotechnology has expanded what can be achieved in our approach to cancer treatment.
The ability to produce and engineer functional nanoparticle formulations to elicit higher …

Imaging metabolic heterogeneity in cancer

D Sengupta, G Pratx - Molecular cancer, 2016 - Springer
As our knowledge of cancer metabolism has increased, it has become apparent that cancer
metabolic processes are extremely heterogeneous. The reasons behind this heterogeneity …

Increased [18F]FDG uptake of radiation-induced giant cells: a single-cell study in lung cancer models

N Das, HTM Nguyen, WJ Lu, A Natarajan, S Khan… - npj Imaging, 2024 - nature.com
Positron emission tomography (PET), a cornerstone in cancer diagnosis and treatment
monitoring, relies on the enhanced uptake of fluorodeoxyglucose ([18F] FDG) by cancer …

Microfluidic synthesis of radiotracers: recent developments and commercialization prospects

M Mc Veigh, LM Bellan - Lab on a Chip, 2024 - pubs.rsc.org
Positron emission tomography (PET) is a powerful diagnostic tool that holds incredible
potential for clinicians to track a wide variety of biological processes using specialized …

Modular low-light microscope for imaging cellular bioluminescence and radioluminescence

TJ Kim, S Türkcan, G Pratx - Nature protocols, 2017 - nature.com
Low-light microscopy methods are receiving increased attention as new applications have
emerged. One such application is to allow longitudinal imaging of light-sensitive cells with …

Ultrahigh resolution radiation imaging system using an optical fiber structure scintillator plate

S Yamamoto, K Kamada, A Yoshikawa - Scientific reports, 2018 - nature.com
High resolution imaging of radiation is required for such radioisotope distribution
measurements as alpha particle detection in nuclear facilities or high energy physics …

Lactic Acid Accumulation in the Tumor Microenvironment Suppresses 18F-FDG Uptake

S Türkcan, L Kiru, DJ Naczynski, LS Sasportas… - Cancer …, 2019 - aacrjournals.org
The process by which tumor cells take up 2-[18F] fluoro-2-deoxy-d-glucose (FDG) is
heterogeneous and influenced by a multitude of factors. In mouse tumor grafts, the core of …

Single-cell tracking with PET using a novel trajectory reconstruction algorithm

KS Lee, TJ Kim, G Pratx - IEEE transactions on medical …, 2014 - ieeexplore.ieee.org
Virtually all biomedical applications of positron emission tomography (PET) use images to
represent the distribution of a radiotracer. However, PET is increasingly used in cell tracking …

Bright Lu2O3:Eu Thin‐Film Scintillators for High‐Resolution Radioluminescence Microscopy

D Sengupta, S Miller, Z Marton, F Chin… - Advanced …, 2015 - Wiley Online Library
The performance of a new thin‐film Lu2O3: Eu scintillator for single‐cell radionuclide
imaging is investigated. Imaging the metabolic properties of heterogeneous cell populations …