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Bridging the gap between tumor-on-chip and clinics: a systematic review of 15 years of studies
Over the past 15 years, the field of oncology research has witnessed significant progress in
the development of new cell culture models, such as tumor-on-chip (ToC) systems. In this …
the development of new cell culture models, such as tumor-on-chip (ToC) systems. In this …
Targeted Cancer Therapy‐on‐A‐Chip
Targeted cancer therapy (TCT) is gaining increased interest because it reduces the risks of
adverse side effects by specifically treating tumor cells. TCT testing has traditionally been …
adverse side effects by specifically treating tumor cells. TCT testing has traditionally been …
Microfluidic vascular models of tumor cell extravasation
Emerging microfluidic disease models have amply demonstrated their value in many fields
of cancer research. These in vitro technologies recapitulate key aspects of metastatic …
of cancer research. These in vitro technologies recapitulate key aspects of metastatic …
PLCB1 Enhances Cell Migration and Invasion in Gastric Cancer Via Regulating Actin Cytoskeletal Remodeling and Epithelial–Mesenchymal Transition
Y Wang, Z Tu, W Zhao, L Wang, J Jiang, L Gu, M Li… - Biochemical …, 2023 - Springer
Abstract Phospholipase C Beta 1 (PLCB1) regulates the abundance of PI (4, 5) P2 in the
plasma membrane and is implicated in various kinds of cancers. This study aimed to …
plasma membrane and is implicated in various kinds of cancers. This study aimed to …
Analysis of EMT induction in a non-invasive breast cancer cell line by mesenchymal stem cell supernatant: Study of 2D and 3D microfluidic based aggregate formation …
S Azadi, E Torkashvand, E Mohammadi… - Life Sciences, 2023 - Elsevier
Abstract Aims The process of Epithelial-to-mesenchymal transition (EMT) as a phenotypic
invasive shift and the factors affecting it, are under extensive research. Application of …
invasive shift and the factors affecting it, are under extensive research. Application of …
[HTML][HTML] Hydrophobic surface induced pro-metastatic cancer cells for in vitro extravasation models
In vitro vascularized cancer models utilizing microfluidics have emerged as a promising tool
for mechanism study and drug screening. However, the lack of consideration and …
for mechanism study and drug screening. However, the lack of consideration and …