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Mechanisms of action of hydroxychloroquine and chloroquine: implications for rheumatology
Despite widespread clinical use of antimalarial drugs such as hydroxychloroquine and
chloroquine in the treatment of rheumatoid arthritis (RA), systemic lupus erythematosus …
chloroquine in the treatment of rheumatoid arthritis (RA), systemic lupus erythematosus …
Safety considerations with chloroquine, hydroxychloroquine and azithromycin in the management of SARS-CoV-2 infection
DN Juurlink - Cmaj, 2020 - Can Med Assoc
Both chloroquine and hydroxychloroquine interfere with ventricular repolarization, leading to
prolongation of the QTc interval and an increased risk of torsades de pointes (TdP). This …
prolongation of the QTc interval and an increased risk of torsades de pointes (TdP). This …
COVID-19 as an acute inflammatory disease
RH Manjili, M Zarei, M Habibi… - The journal of immunology, 2020 - journals.aai.org
Abstract The 2019 coronavirus disease (COVID-19) pandemic caused by the virus severe
acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has created an unprecedented …
acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has created an unprecedented …
Recommendations on screening for chloroquine and hydroxychloroquine retinopathy (2016 revision)
Background The American Academy of Ophthalmology recommendations on screening for
chloroquine (CQ) and hydroxychloroquine (HCQ) retinopathy are revised in light of new …
chloroquine (CQ) and hydroxychloroquine (HCQ) retinopathy are revised in light of new …
Antivirals against coronaviruses: candidate drugs for SARS-CoV-2 treatment?
Coronaviruses (CoVs) are a group of viruses from the family Coronaviridae that can infect
humans and animals, causing mild to severe diseases. The ongoing pandemic of severe …
humans and animals, causing mild to severe diseases. The ongoing pandemic of severe …
Hepatic consequences of COVID-19 infection. Lap** or biting?
P Portincasa, M Krawczyk, A Machill, F Lammert… - European journal of …, 2020 - Elsevier
The outbreak of coronavirus disease 2019 (COVID-19) starting last December in China
placed emphasis on liver involvement during infection. This review discusses the underlying …
placed emphasis on liver involvement during infection. This review discusses the underlying …
Hydroxychloroquine blood levels predict hydroxychloroquine retinopathy
M Petri, M Elkhalifa, J Li, LS Magder… - Arthritis & …, 2020 - Wiley Online Library
Objective In 2016, the American Academy of Ophthalmology (AAO) changed the
recommended daily dose of hydroxychloroquine (HCQ) from 6.5 mg/kg to< 5 mg/kg …
recommended daily dose of hydroxychloroquine (HCQ) from 6.5 mg/kg to< 5 mg/kg …
COVID-19 prevention and treatment: A critical analysis of chloroquine and hydroxychloroquine clinical pharmacology
COVID-19 prevention and treatment: A critical analysis of chloroquine and
hydroxychloroquine clinical pharmacology | PLOS Medicine Skip to main content …
hydroxychloroquine clinical pharmacology | PLOS Medicine Skip to main content …
[HTML][HTML] Disease-drug and drug-drug interaction in COVID-19: Risk and assessment
COVID-19 is announced as a global pandemic in 2020. Its mortality and morbidity rate are
rapidly increasing, with limited medications. The emergent outbreak of COVID-19 prompted …
rapidly increasing, with limited medications. The emergent outbreak of COVID-19 prompted …
Pharmacogenomics of COVID-19 therapies
A new global pandemic of coronavirus disease 2019 (COVID-19) has resulted in high
mortality and morbidity. Currently numerous drugs are under expedited investigations …
mortality and morbidity. Currently numerous drugs are under expedited investigations …