Anatomy of four human Argonaute proteins

K Nakanishi - Nucleic acids research, 2022 - academic.oup.com
MicroRNAs (miRNAs) bind to complementary target RNAs and regulate their gene
expression post-transcriptionally. These non-coding regulatory RNAs become functional …

The functional role of long non-coding RNA in human carcinomas

EA Gibb, CJ Brown, WL Lam - Molecular cancer, 2011 - Springer
Long non-coding RNAs (lncRNAs) are emerging as new players in the cancer paradigm
demonstrating potential roles in both oncogenic and tumor suppressive pathways. These …

Extensive terminal and asymmetric processing of small RNAs from rRNAs, snoRNAs, snRNAs, and tRNAs

Z Li, C Ender, G Meister, PS Moore… - Nucleic acids …, 2012 - academic.oup.com
Deep sequencing studies frequently identify small RNA fragments of abundant RNAs. These
fragments are thought to represent degradation products of their precursors. Using …

Viral microRNA targetome of KSHV-infected primary effusion lymphoma cell lines

E Gottwein, DL Corcoran, N Mukherjee, RL Skalsky… - Cell host & …, 2011 - cell.com
Primary effusion lymphoma (PEL) is caused by Kaposi's sarcoma-associated herpesvirus
(KSHV) and frequently also harbors Epstein-Barr virus (EBV). The expression of KSHV-and …

A sensitive non-radioactive northern blot method to detect small RNAs

SW Kim, Z Li, PS Moore, AP Monaghan… - Nucleic acids …, 2010 - academic.oup.com
The continuing discoveries of potentially active small RNAs at an unprecedented rate using
high-throughput sequencing have raised the need for methods that can reliably detect and …

Small RNA profiling of Dengue virus-mosquito interactions implicates the PIWI RNA pathway in anti-viral defense

AM Hess, AN Prasad, A Ptitsyn, GD Ebel, KE Olson… - BMC microbiology, 2011 - Springer
Abstract Background Small RNA (sRNA) regulatory pathways (SRRPs) are important to anti-
viral defence in mosquitoes. To identify critical features of the virus infection process in …

Ago HITS-CLIP expands understanding of Kaposi's sarcoma-associated herpesvirus miRNA function in primary effusion lymphomas

I Haecker, LA Gay, Y Yang, J Hu, AM Morse… - 2012 - journals.plos.org
KSHV is the etiological agent of Kaposi's sarcoma (KS), primary effusion lymphoma (PEL),
and a subset of multicentricCastleman's disease (MCD). The fact that KSHV-encoded …

Dicer-2-and Piwi-mediated RNA interference in Rift Valley fever virus-infected mosquito cells

P Leger, E Lara, B Jagla, O Sismeiro… - Journal of …, 2013 - Am Soc Microbiol
Rift Valley fever virus (RVFV) is a Phlebovirus (Bunyaviridae family) transmitted by
mosquitoes. It infects humans and ruminants, causing dramatic epidemics and epizootics in …

Determining the defining lengths between mature microRNAs/small interfering RNAs and tinyRNAs

GY Sim, AC Kehling, MS Park, C Divoky, H Zhang… - Scientific Reports, 2023 - nature.com
MicroRNAs (miRNAs) and small interfering RNAs (siRNAs) are loaded into Argonaute
(AGO) proteins, forming RNA-induced silencing complexes (RISCs). The assembly process …

RNA in pieces

AC Tuck, D Tollervey - Trends in genetics, 2011 - cell.com
Eukaryotic genomes accommodate numerous types of information within diverse DNA and
RNA sequence elements. At many loci, these elements overlap and the same sequence is …