Alzheimer's disease (AD) is a common form of dementia in aged people, which is defined by
two pathological characteristics: β-amyloid protein (Aβ) deposition and tau …

In this review, we present a timeline that shows the origin of mixed chelate copper (II)
complexes, registered as Mark Title Casiopeínas®, as the first copper (II) compounds …

The family of anticancer complexes that include the transition metal copper known as
Casiopeínas® shows promising results. Two of these complexes are currently in clinical …

Two new 'hybrid'metallodrugs of Au (III)(AuTAML) and Cu (II)(CuTAML) were designed
featuring a tamoxifen-derived pharmacophore to ideally synergize the anticancer activity of …

Casiopeinas are a family of mixed chelate copper (II) complexes with antiproliferative and
antineoplastic activities, results that have positioned them as an alternative for cancer …

Casiopeinas are a family of copper (II) coordination compounds that have shown an
important antineoplastic effect and low toxicity in normal cells. These compounds induce …

Here, we report four new heteroleptic Cu (II) complexes with the formula [Cu
(bipy)(2H4MeBz)] NO 3 (1),[Cu (phen)(2H4MeBz)] NO 3 (2),[Cu (bipy)(2H4OcBz)] NO 3 (3) …

Dimethyl 6-(pyrazine-2-yl) pyridine-3, 4-dicarboxylate (py-2pz) was used as a ligand for the
synthesis of new copper (II) and silver (I) complexes,[CuCl2 (py-2pz)] 2 (1),[Cu …

The family of Copper (II) coordination compounds Casiopeínas®(Cas) has shown
antiproliferative activity in several tumour lines by oxidative cellular damage and …

Herein, we present the synthesis, characterization, DFT calculations and in vitro evaluation
of antiproliferative activity against HeLa and MCF-7 cancer tumor cell lines of three novel …