Diabetic encephalopathy (DE), a significant micro-complication of diabetes, manifests as
neurochemical, structural, behavioral, and cognitive alterations. This condition is especially …

Simple Summary Cancer mortalities are growing at an alarming pace around the globe, a
fact related to challenges, such as side effects, selectivity, and resistance, accompanied by …

Among the multiple kinds of neuronal cell death triggered by traumatic brain injury (TBI),
ferroptosis, an iron-dependent lipid peroxidative regulatory cell death, has a critical role …

Traumatic brain injury (TBI) is a serious health issue with a high incidence, high morbidity,
and high mortality that poses a large burden on society. Further understanding of the …

Despite advancements in cancer management, tumor relapse and metastasis are
associated with poor outcomes in many cancers. Over the past decade, oncogene-driven …

A novel series of thiazole derivatives with pyrazole scaffold 16a-l as hybrid rosiglitazone/
celecoxib analogs was designed, synthesized and tested for its PPAR-γ activation, α …

Peroxisome proliferator-activator receptors α/δ (PPARα/δ) are regarded as potential
therapeutic targets for nonalcoholic steatohepatitis (NASH). However, PPARα/δ dual agonist …

The present study investigates whether hesperetin, a citrus flavonoid, can encounter
advanced glycation end-product (AGE)-induced Alzheimer's disease-like pathophysiological …

One of the utmost frequently emerging neurodegenerative diseases, Parkinson's disease
(PD) must be comprehended through the forfeit of dopamine (DA)-generating nerve cells in …

Introduction The analysis of the role of the mitochondria in oxidative damage and skin aging
has been a significant aspect of dermatological research. Mitochondria generate most …