Free radical properties, source and targets, antioxidant consumption and health

G Martemucci, C Costagliola, M Mariano, L D'andrea… - Oxygen, 2022 - mdpi.com
Free radicals have acquired growing importance in the fields of biology and medicine. They
are produced during many different endogenous and exogenous processes. Mitochondria …

A comprehensive review on lipid oxidation in meat and meat products

R Domínguez, M Pateiro, M Gagaoua, FJ Barba… - Antioxidants, 2019 - mdpi.com
Meat and meat products are a fundamental part of the human diet. The protein and vitamin
content, as well as essential fatty acids, gives them an appropriate composition to complete …

Terpenoids and polyphenols as natural antioxidant agents in food preservation

I Gutiérrez-del-Río, S López-Ibáñez… - Antioxidants, 2021 - mdpi.com
Synthetic antioxidant food additives, such as BHA, BHT and TBHQ, are going through a
difficult time, since these products generate a negative perception in consumers. This has …

Multiscale simulations of biological membranes: the challenge to understand biological phenomena in a living substance

G Enkavi, M Javanainen, W Kulig, T Róg… - Chemical …, 2019 - ACS Publications
Biological membranes are tricky to investigate. They are complex in terms of molecular
composition and structure, functional over a wide range of time scales, and characterized by …

Nanoparticles containing oxidized cholesterol deliver mRNA to the liver microenvironment at clinically relevant doses

K Paunovska, AJ Da Silva Sanchez… - Advanced …, 2019 - Wiley Online Library
Using mRNA to produce therapeutic proteins is a promising approach to treat genetic
diseases. However, systemically delivering mRNA to cell types besides hepatocytes …

The role of oxysterols in human cancer

A Kloudova, FP Guengerich, P Soucek - Trends in Endocrinology & …, 2017 - cell.com
Oxysterols are oxygenated derivatives of cholesterol formed in the human body or ingested
in the diet. By modulating the activity of many proteins [eg, liver X receptors (LXRs), oxysterol …

Impact of oxysterols on cell death, proliferation, and differentiation induction: current status

FA de Freitas, D Levy, A Zarrouk, G Lizard… - Cells, 2021 - mdpi.com
Oxysterols are oxidized derivatives of cholesterol produced by enzymatic activity or non-
enzymatic pathways (auto-oxidation). The oxidation processes lead to the synthesis of about …

Lipid oxidation derived aldehydes and oxysterols between health and disease

B Sottero, G Leonarduzzi, G Testa… - European journal of …, 2019 - Wiley Online Library
Non‐enzymatic and enzymatic oxidation of lipids has long been a primary issue in human
pathophysiology, with special emphasis on diet‐and nutrition‐related aspects. While there is …

The Niemann-Pick type diseases–A synopsis of inborn errors in sphingolipid and cholesterol metabolism

FW Pfrieger - Progress in lipid research, 2023 - Elsevier
Disturbances of lipid homeostasis in cells provoke human diseases. The elucidation of the
underlying mechanisms and the development of efficient therapies represent formidable …

Contribution of cholesterol and oxysterols to the pathophysiology of Parkinson's disease

M Doria, L Maugest, T Moreau, G Lizard… - Free Radical Biology and …, 2016 - Elsevier
Neurodegenerative diseases are a major public health issue worldwide. Some countries,
including France, have engaged in research into the causes of Parkinson's disease …