The availability of public genomic resources can greatly assist biodiversity assessment,
conservation, and restoration efforts by providing evidence for scientifically informed …

Long-read sequencing technologies have now reached a level of accuracy and yield that
allows their application to variant detection at a scale of tens to thousands of samples …

The goals of the Earth Biogenome Project—to sequence the genomes of all eukaryotic life
on earth—are as daunting as they are ambitious. The Darwin Tree of Life Project was …

November 2020 marked 2 y since the launch of the Earth BioGenome Project (EBP), which
aims to sequence all known eukaryotic species in a 10-y timeframe. Since then, significant …

Motivation Rapid development in long-read sequencing and scaffolding technologies is
accelerating the production of reference-quality assemblies for large eukaryotic genomes …

The definition of epigenetics refers that molecular modifications on DNA that can regulate
gene activity are independent of DNA sequence and mitotically stable. Notably, epigenetics …

Almost 20 years have passed since the first reference genome assemblies were published
for Plasmodium falciparum, the deadliest malaria parasite, and Anopheles gambiae, the …

Long-read sequencing is driving rapid progress in genome assembly across all major
groups of life, including species of the family Drosophilidae, a longtime model system for …

Bisulfite sequencing is a powerful technique to detect 5-methylcytosine in DNA that has
immensely contributed to our understanding of epigenetic regulation in plants and animals …

Life on Earth has evolved from initial simplicity to the astounding complexity we experience
today. Bacteria and archaea have largely excelled in metabolic diversification, but …