Current trends in toxicity assessment of herbal medicines: A narrative review

A Jităreanu, A Trifan, M Vieriu, IC Caba, I Mârțu… - Processes, 2022 - mdpi.com
Even in modern times, the popularity level of medicinal plants and herbal medicines in
therapy is still high. The World Health Organization estimates that 80% of the population in …

The effectiveness of Bacopamonnieri (Linn.) Wettst. as a nootropic, neuroprotective, or antidepressant supplement: analysis of the available clinical data

JM Brimson, S Brimson, MI Prasanth, P Thitilertdecha… - Scientific reports, 2021 - nature.com
Abstract Bacopa monnieri (Linn.) Wettst. has been used in traditional medicine as a drug to
enhance and improve memory. In this regard, this study aims to provide B. monnieri's …

[HTML][HTML] Plant extracts as possible agents for Sequela of cancer therapies and cachexia

J Lee, MI Jeong, HR Kim, H Park, WK Moon, B Kim - Antioxidants, 2020 - mdpi.com
Cancer is a leading cause of the death worldwide. Since the National Cancer Act in 1971,
various cancer treatments were developed including chemotherapy, surgery, radiation …

[HTML][HTML] Gingerol inhibits cisplatin-induced acute and delayed emesis in rats and minks by regulating the central and peripheral 5-HT, SP, and DA systems

L Tian, W Qian, Q Qian, W Zhang, X Cai - Journal of natural medicines, 2020 - Springer
Gingerol, a biologically active component in ginger, has shown antiemetic properties. Our
study aimed to explore the underlying mechanisms of gingerol on protecting rats and minks …

A bacosides containing Bacopa monnieri extract alleviates allodynia and hyperalgesia in the chronic constriction injury model of neuropathic pain in rats

M Shahid, F Subhan, N Ahmad, I Ullah - BMC complementary and …, 2017 - Springer
Background The current therapy of neuropathic pain is inadequate and is limited by the
extent of pain relief and the occurrence of dose dependant side effects. Insufficient control of …

Efficacy of a topical gabapentin gel in a cisplatin paradigm of chemotherapy-induced peripheral neuropathy

M Shahid, F Subhan, N Ahmad, RDE Sewell - BMC Pharmacology and …, 2019 - Springer
Background Chemotherapy induced peripheral neuropathy (CIPN) has been attributed to
chemotherapeutic agents such as cisplatin which adversely affect disease outcome leading …

Anti-emetic mechanisms of zingiber officinale against cisplatin induced emesis in the pigeon; behavioral and neurochemical correlates

I Ullah, F Subhan, M Ayaz, R Shah, G Ali… - … and Alternative Medicine, 2015 - Springer
Background Zingiber officinale (ZO, family Zingiberaceae) has been reported for its
antiemetic activity against cancer chemotherapy induced emesis in animal models and in …

Synthetic and natural antioxidants attenuate cisplatin-induced vomiting

J Alam, F Subhan, I Ullah, M Shahid, G Ali… - BMC Pharmacology and …, 2017 - Springer
Background Synthetic and natural antioxidants including Bacopa monnieri (L.) Pennell
(Scrophulariaceae) which also possess anti-dopaminergic properties, have been proposed …

A re-consideration of neural/receptor mechanisms in chemotherapy-induced nausea and vomiting: Current scenario and future perspective

I Ullah, M Ayaz - Pharmacological Reports, 2023 - Springer
The neural mechanisms and the receptors behind the course of chemotherapy-induced
nausea and vomiting (CINV) are well described and considered mechanistically …

The antioxidant N-(2-mercaptopropionyl)-glycine (tiopronin) attenuates expression of neuropathic allodynia and hyperalgesia

M Shahid, F Subhan, NU Islam, N Ahmad… - Naunyn-Schmiedeberg's …, 2021 - Springer
The current pharmacotherapy of neuropathic pain is inadequate as neuropathic pain
involves varied clinical manifestations with multifactorial etiology, modulated by a cascade of …