Tumour necrosis factor gene polymorphism and disease prevalence

T Qidwai, F Khan - Scandinavian journal of immunology, 2011 - Wiley Online Library
Tumour necrosis factor (TNF), an important proinflammatory cytokine, plays a role in the
regulation of cell differentiation, proliferation and death, as well as in inflammation, innate …

Demographic, clinical and genetic factors associated with COVID-19 disease susceptibility and mortality in a Kurdish population

SW Smail, E Babaei, K Amin - Annals of Saudi Medicine, 2023 - annsaudimed.net
BACKGROUND: Coronavirus disease 2019 (COVID-19) is a devastating pandemic that
causes disease with a variability in susceptibility and mortality based on variants of various …

Polymorphisms within the tumor necrosis factor-alpha gene is associated with preeclampsia in taiwanese han populations

CW Lin, CH Chen, MH Wu, FM Chang, L Kang - Biomedicines, 2023 - mdpi.com
Preeclampsia (PE) occurs in women pregnant for more than 20 weeks with de novo
hypertension and proteinuria, and is a devastating disease in maternal–fetal medicine …

Evaluation of tumor necrosis factor alpha polymorphism frequencies in endometriosis

R Abutorabi, A Baradaran, FS Mostafavi… - … journal of fertility & …, 2015 - pmc.ncbi.nlm.nih.gov
Background The pro-inflammatory cytokine, tumor necrosis factor-alpha (TNF-α), is a
pathogenic element for a number of disorders. Previous studies have reported that the-1031 …

Exploring pharmacogenetic variants for predicting response to anti-TNF therapy in autoimmune diseases: A meta-analysis

C Antonatos, EF Stavrou, E Evangelou… - …, 2021 - Taylor & Francis
Aim: The aim of this study is to explore how SNPs may affect the response to anti-TNF-α
therapy in the major autoimmune diseases, such as psoriasis, rheumatoid arthritis …

Association of single nucleotide polymorphisms in TNF-α (− 308G/A and− 238G/A) to dengue: Case-control and meta-analysis study

NC Dos Santos, TN Gomes, IA de Fontes Gois… - Cytokine, 2020 - Elsevier
Dengue is an acute viral disease whose clinical condition is related to the interaction of
factors related to the Dengue virus (DENV), environment and the host, with the immunity of …

Association analysis between-308G/A and-238G/A TNF-alpha gene promoter polymorphisms and insulin resistance in Mexican women with gestational diabetes …

JM Guzmán-Flores, M Escalante… - Journal of …, 2013 - journals.sagepub.com
Background Gestational diabetes mellitus (GDM) is characterized by insulin resistance. It
has been described that tumor necrosis factor α (TNF-α) plays a key role in the pathogenesis …

Association of tumor necrosis factor alpha promoter polymorphism (TNF-α 238 G/A and TNF-α 308 G/A) with diabetic mellitus, diabetic retinopathy and diabetic …

N Meng, Y Zhang, H Li, J Ma, Y Qu - Current eye research, 2014 - Taylor & Francis
Aim: To examine the association between tumor necrosis factor alpha (TNF-α)
polymorphism and risk for diabetic mellitus (DM), diabetic retinopathy (DR) and diabetic …

TNF 308 G/A polymorphism and type 1 diabetes: a meta-analysis

RN Feng, Y Li, CH Sun - Diabetes research and clinical practice, 2009 - Elsevier
We conducted a meta-analysis to examine the association between TNF 308 G/A
polymorphism and risk for T1DM. Eleven reports were identified. Our study confirmed that a …

Tumor necrosis factor–associated susceptibility to type 1 diabetes is caused by linkage disequilibrium with HLA-DR3 haplotypes

N Kumar, G Kaur, N Tandon, N Mehra - Human immunology, 2012 - Elsevier
Tumor necrosis factor-α (TNF-α) is an important proinflammatory cytokine involved in the
pathogenesis of autoimmune type 1 diabetes (T1D). The TNF gene locus is located in the …